More than meets the eye: The role of microglia in healthy and diseased retina

E Murenu, MJ Gerhardt, M Biel… - Frontiers in …, 2022 - frontiersin.org
Microglia are the main resident immune cells of the nervous system and as such they are
involved in multiple roles ranging from tissue homeostasis to response to insults and circuit …

Microbiome dysbiosis: a pathological mechanism at the intersection of obesity and glaucoma

S Pezzino, M Sofia, LP Greco, G Litrico… - International Journal of …, 2023 - mdpi.com
The rate at which obesity is becoming an epidemic in many countries is alarming. Obese
individuals have a high risk of developing elevated intraocular pressure and glaucoma …

Deep learning-based glaucoma detection with cropped optic cup and disc and blood vessel segmentation

MT Islam, ST Mashfu, A Faisal, SC Siam… - Ieee …, 2021 - ieeexplore.ieee.org
Glaucoma is an irreversible neurodegenerative disease, where intraocular hypertension is
developed due to the increased aqueous humor and blockage of the drainage system …

Glaucoma detection with retinal fundus images using segmentation and classification

T Shyamalee, D Meedeniya - Machine Intelligence Research, 2022 - Springer
Glaucoma is a prevalent cause of blindness worldwide. If not treated promptly, it can cause
vision and quality of life to deteriorate. According to statistics, glaucoma affects …

Brain-derived neurotrophic factor-mediated neuroprotection in glaucoma: a review of current state of the art

L Lambuk, MA Mohd Lazaldin, S Ahmad… - Frontiers in …, 2022 - frontiersin.org
Retinal ganglion cells (RGCs) are neurons of the visual system that are responsible for
transmitting signals from the retina to the brain via the optic nerve. Glaucoma is an optic …

Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update

R Baghban, MR Talebnejad, A Meshksar… - Journal of …, 2023 - Springer
Despite the existence of numerous eye drops in the market, most of them are not sufficiently
effective because of quick clearance and the barriers within the eye. To increase the delivery …

Smart contact lenses—A step towards non-invasive continuous eye health monitoring

NL Kazanskiy, SN Khonina, MA Butt - Biosensors, 2023 - mdpi.com
According to the age-old adage, while eyes are often considered the gateway to the soul,
they might also provide insights into a more pragmatic aspect of our health: blood sugar …

Immunomodulatory and antioxidant drugs in glaucoma treatment

F Buonfiglio, N Pfeiffer, A Gericke - Pharmaceuticals, 2023 - mdpi.com
Glaucoma, a group of diseases characterized by progressive retinal ganglion cell loss,
cupping of the optic disc, and a typical pattern of visual field defects, is a leading cause of …

A promising 'single'and 'dual'drug-nanocomposite enriched contact lens for the management of glaucoma in response to the tear fluid enzyme

BN Kumara, K Velmurugan, MV Ghate… - Journal of Materials …, 2024 - pubs.rsc.org
Glaucoma is a neurodegenerative condition that results in the damage of retinal ganglion
cells due to elevated intraocular pressure (IOP). To curtail the limitations associated with …

Current situation and progress of drugs for reducing intraocular pressure

P Liu, F Wang, Y Song, M Wang… - … advances in chronic …, 2022 - journals.sagepub.com
Glaucoma, the most common cause of irreversible blindness worldwide, usually causes
characteristic optic nerve damage. Pathological intraocular pressure (IOP) elevation is a …