Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods

S Jordaens, K Zwaenepoel, W Tjalma… - … Journal of Cancer, 2023 - Wiley Online Library
The aim of this review was to explore the status of urine sampling as a liquid biopsy for
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …

Circulating and urinary tumour DNA in urothelial carcinoma—Upper tract, lower tract and metastatic disease

KM Rose, HL Huelster, JJ Meeks, BM Faltas… - Nature Reviews …, 2023 - nature.com
Precision medicine has transformed the way urothelial carcinoma is managed. However,
current practices are limited by the availability of tissue samples for genomic profiling and …

Fragmentation patterns and personalized sequencing of cell‐free DNA in urine and plasma of glioma patients

F Mouliere, CG Smith, K Heider, J Su… - EMBO molecular …, 2021 - embopress.org
Glioma‐derived cell‐free DNA (cfDNA) is challenging to detect using liquid biopsy because
quantities in body fluids are low. We determined the glioma‐derived DNA fraction in …

[HTML][HTML] based microfluidic devices: Fabrication, detection, and significant applications in various fields

S Das, Gagandeep, R Bhatia - Reviews in Analytical Chemistry, 2022 - degruyter.com
Paper is the most abundant and inexpensive polymeric structure of cellulose available.
Paper has micro-porous capillary-like networks which are responsible for flow of solvents …

[HTML][HTML] Detection of colorectal cancer in urine using DNA methylation analysis

S Bach, I Paulis, NR Sluiter, M Tibbesma, I Martin… - Scientific reports, 2021 - nature.com
Colorectal cancer (CRC) is the second leading cause for cancer-related death globally.
Clinically, there is an urgent need for non-invasive CRC detection. This study assessed the …

[HTML][HTML] Bladder cancer detection in urine using DNA methylation markers: a technical and prospective preclinical validation

AE Hentschel, IJ Beijert, J Bosschieter, PC Kauer… - Clinical …, 2022 - Springer
Background The development of accurate urinary biomarkers for non-invasive and cost-
effective detection of primary and recurrent bladder tumours is recognized as one of the …

[HTML][HTML] Non-invasive detection of endometrial cancer by DNA methylation analysis in urine

R van den Helder, BMM Wever, NE van Trommel… - Clinical …, 2020 - Springer
Background The incidence of endometrial cancer is rising, and current diagnostics often
require invasive biopsy procedures. Urine may offer an alternative sample type, which is …

[HTML][HTML] The MAL family of proteins: normal function, expression in cancer, and potential use as cancer biomarkers

L Labat-de-Hoz, A Rubio-Ramos, I Correas, MA Alonso - Cancers, 2023 - mdpi.com
Simple Summary The use of biomarkers can provide information about the outcome of
cancer patients, the type of tumor, its malignant potential and the risk of recurrence, and may …

[HTML][HTML] Urinary miRNAs as a diagnostic tool for bladder cancer: a systematic review

AM Grimaldi, C Lapucci, M Salvatore, M Incoronato… - Biomedicines, 2022 - mdpi.com
Bladder cancer is the 10th most common cancer type worldwide. Cystoscopy represents the
gold standard for bladder cancer diagnosis, but this procedure is invasive and painful …

[HTML][HTML] Diagnostic potential of circulating tumor cells, urinary microRNA, and urinary cell-free DNA for bladder cancer: A review

D Koguchi, K Matsumoto, I Shiba, T Harano… - International Journal of …, 2022 - mdpi.com
Early detection of primary bladder cancer (BCa) is vital, because stage and grade have
been generally accepted not only as categorical but also as prognostic factors in patients …