Neoplasia-associated chromosome translocations resulting in gene truncation
I Panagopoulos, S Heim - Cancer Genomics & Proteomics, 2022 - cgp.iiarjournals.org
Chromosomal translocations in cancer as well as benign neoplasias typically lead to the
formation of fusion genes. Such genes may encode chimeric proteins when two protein …
formation of fusion genes. Such genes may encode chimeric proteins when two protein …
[HTML][HTML] The MOZ-BRPF1 acetyltransferase complex in epigenetic crosstalk linked to gene regulation, development, and human diseases
T Viita, J Côté - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
Acetylation of lysine residues on histone tails is an important post-translational modification
(PTM) that regulates chromatin dynamics to allow gene transcription as well as DNA …
(PTM) that regulates chromatin dynamics to allow gene transcription as well as DNA …
[HTML][HTML] Case Report: A Unique Case of Pediatric Central Nervous System Embryonal Tumor Harboring the CIC–LEUTX Fusion, Germline NBN Variant and Somatic TSC2 …
W Hu, J Wang, L Yuan, X Zhang, Y Ji, C Song… - Frontiers in …, 2020 - frontiersin.org
Central nervous system (CNS) embryonal tumors (WHO grade IV) are a heterogeneous
group of rare, poorly differentiated neuroepithelial malignant neoplasms that commonly …
group of rare, poorly differentiated neuroepithelial malignant neoplasms that commonly …
A novel BRD4‐LEUTX fusion in a pediatric sarcoma with epithelioid morphology and diffuse S100 expression
S Barresi, I Giovannoni, S Rossi… - Genes …, 2021 - Wiley Online Library
Malignant epithelioid soft tissue tumors encompass a wide spectrum of lesions. Among
them, Epithelioid Malignant Peripheral Nerve Sheath Tumors (MPNST) constitute a distinct …
them, Epithelioid Malignant Peripheral Nerve Sheath Tumors (MPNST) constitute a distinct …
Therapy-related myeloid leukemia with the translocation t (8; 19)(p11; q13) leading to a KAT6A-LEUTX fusion gene
I Panagopoulos, K Andersen, LF Ramslien… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: The chromosome translocation t (8; 19)(p11; q13) has been reported in
only six acute myeloid leukemia (AML) patients. We here present the genetic and clinical …
only six acute myeloid leukemia (AML) patients. We here present the genetic and clinical …
[HTML][HTML] KAT6A:: EP300 fusion in congenital myeloid sarcoma: Yet another novel molecular marker indicating spontaneous remission?: A case report
SH Vasanna, SD Shah, BR Rohr, B Roche… - Medicine, 2023 - journals.lww.com
Rationale: Acute myeloid leukemia (AML)/myeloid sarcoma (MS) is risk-stratified based on
cytogenetics. Although most congenital AML/MS have a dismal prognosis, certain genetic …
cytogenetics. Although most congenital AML/MS have a dismal prognosis, certain genetic …
[引用][C] KAT6A:: EP300 fusion in congenital myeloid sarcoma: Yet another novel molecular marker indicating spontaneous remission?
H Meyerson, I Pateva - 2023 - europepmc.org
Rationale: Acute myeloid leukemia (AML)/myeloid sarcoma (MS) is risk-stratified based on
cytogenetics. Although most congenital AML/MS have a dismal prognosis, certain genetic …
cytogenetics. Although most congenital AML/MS have a dismal prognosis, certain genetic …