Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …

Innate immunity is fundamental to our defense against microorganisms. Physiologically, the
intravascular innate immune system acts as a purging system that identifies and removes …

Similar to dementia, the risk for developing type 2 diabetes mellitus (T2DM) increases with
age, and T2DM also increases the risk for dementia, particularly Alzheimer's disease (AD) …

A ten-week feeding trial on Monopterus albus (initial weight 24.02±0.02 g) was conducted to
evaluate effects of four isonitrogenous and isoenergetic diets in which different proportions …

Complement system aberrations have been identified as pathophysiological mechanisms in
a number of diseases and pathological conditions either directly or indirectly. Examples of …

Despite recent medical advances, atherosclerosis is a global burden accounting for
numerous deaths and hospital admissions. Immune-mediated inflammation is a major …

Nonalcoholic fatty liver disease (NAFLD) has become a leading cause of chronic liver
diseases globally. NAFLD includes a range of hepatic manifestations, starting with liver …

Background Neuroinflammation is emerging as an important pathological process in
frontotemporal dementia (FTD), but biomarkers are lacking. We aimed to determine the …

Abundant reports have shown that there is a strong relationship between C3 and C3a-
desArg levels, adipose tissue, and risk factors for cardiovascular disease, metabolic …

As the common factor linking adipose tissue to the metabolic context of obesity, insulin
resistance and atherosclerosis are associated with a low-grade chronic inflammatory status …