Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature

N Muvhulawa, PV Dludla, K Ziqubu… - Pharmacological …, 2022 - Elsevier
Chronic inflammation remains an essential complication in the pathogenesis and
aggravation of metabolic diseases. There is a growing interest in the use of medicinal plants …

[HTML][HTML] Diet in the management of type 2 diabetes: umbrella review of systematic reviews with meta-analyses of randomised controlled trials

E Szczerba, J Barbaresko, T Schiemann… - BMJ …, 2023 - ncbi.nlm.nih.gov
Diet in the management of type 2 diabetes: umbrella review of systematic reviews with meta-analyses
of randomised controlled trials - PMC Back to Top Skip to main content NIH NLM Logo Access …

Isoorientin: A dietary flavone with the potential to ameliorate diverse metabolic complications

K Ziqubu, PV Dludla, E Joubert, CJF Muller… - Pharmacological …, 2020 - Elsevier
Isoorientin is a natural C-glucosyl flavone that is generating a lot of interest due to its
multiple pharmacological activities. Increasing experimental data have shown that the robust …

Neuroprotective and anxiolytic potential of green rooibos (Aspalathus linearis) polyphenolic extract

V López, G Cásedas, K Petersen-Ross, Y Powrie… - Food & Function, 2022 - pubs.rsc.org
South African rooibos (Aspalathus linearis) tea is globally consumed for its health benefits
and caffeine free nature, but no information is available on the neuroprotective capacity of …

[HTML][HTML] Network Pharmacology- and Molecular Dynamics Simulation-Based Bioprospection of Aspalathus linearis for Type-2 Diabetes Care

A Akoonjee, A Rampadarath, CE Aruwa, TA Ajiboye… - Metabolites, 2022 - mdpi.com
The medicinal herb Aspalathus linearis (rooibos) is globally recognized in type-2 diabetes
mellitus (T2DM) treatment due to its known and distinctive compounds. This work utilized …

PLGA@ IL-8 nanoparticles-loaded acellular dermal matrix as a delivery system for exogenous MSCs in diabetic wound healing

Y Zhang, W Jiang, L Kong, J Fu, Q Zhang… - International Journal of …, 2023 - Elsevier
Diabetic chronic wounds are not only accompanied by inflammation and ulcers but also
cause amputation when they develop into severe diabetic foot. Mesenchymal stem cells …

[HTML][HTML] Rooibos, a supportive role to play during the COVID-19 pandemic?

NS Abdul, JL Marnewick - Journal of functional foods, 2021 - Elsevier
This article presents the potential health benefits of Rooibos to be considered a support
during the COVID-19 pandemic. The recent pandemic of COVID-19 has led to severe …

[HTML][HTML] Advancement of analytical techniques in some South African commercialized medicinal plants: Current and future perspectives

NA Masondo, NP Makunga - South African Journal of Botany, 2019 - Elsevier
As the use of medicinal plants continues to gain popularity worldwide, there is dire need for
herbal medicines to be guaranteed in their safety and efficacy. South Africa has a largely …

Aspalathin protects insulin‐producing β cells against glucotoxicity and oxidative stress‐induced cell death

C Moens, M Bensellam, E Himpe… - Molecular nutrition & …, 2020 - Wiley Online Library
Scope Aspalathin, the main polyphenolic phytochemical of rooibos (Aspalathus linearis),
has been attributed with health promoting properties, including a glucose lowering effect that …

Green rooibos extract attenuates high glucose induced oxidative stress in a human derived (HepG2) liver cell line

NS Abdul, JL Marnewick - South African Journal of Botany, 2022 - Elsevier
The exposure of hepatocytes to high concentrations of glucose results in a glucotoxic
environment and ensuing hepatocellular injury, often due to oxidative stress. The popularly …