[HTML][HTML] Graph neural networks and their current applications in bioinformatics

XM Zhang, L Liang, L Liu, MJ Tang - Frontiers in genetics, 2021 - frontiersin.org
Graph neural networks (GNNs), as a branch of deep learning in non-Euclidean space,
perform particularly well in various tasks that process graph structure data. With the rapid …

Graph representation learning in bioinformatics: trends, methods and applications

HC Yi, ZH You, DS Huang… - Briefings in …, 2022 - academic.oup.com
Graph is a natural data structure for describing complex systems, which contains a set of
objects and relationships. Ubiquitous real-life biomedical problems can be modeled as …

Predicting drug–disease associations through layer attention graph convolutional network

Z Yu, F Huang, X Zhao, W Xiao… - Briefings in …, 2021 - academic.oup.com
Background: Determining drug–disease associations is an integral part in the process of
drug development. However, the identification of drug–disease associations through wet …

A weighted bilinear neural collaborative filtering approach for drug repositioning

Y Meng, C Lu, M Jin, J Xu, X Zeng… - Briefings in …, 2022 - academic.oup.com
Drug repositioning is an efficient and promising strategy for traditional drug discovery and
development. Many research efforts are focused on utilizing deep-learning approaches …

Drug repositioning based on the heterogeneous information fusion graph convolutional network

L Cai, C Lu, J Xu, Y Meng, P Wang, X Fu… - Briefings in …, 2021 - academic.oup.com
In silico reuse of old drugs (also known as drug repositioning) to treat common and rare
diseases is increasingly becoming an attractive proposition because it involves the use of de …

Updated review of advances in microRNAs and complex diseases: taxonomy, trends and challenges of computational models

L Huang, L Zhang, X Chen - Briefings in Bioinformatics, 2022 - academic.oup.com
Since the problem proposed in late 2000s, microRNA–disease association (MDA)
predictions have been implemented based on the data fusion paradigm. Integrating diverse …

DSTG: deconvoluting spatial transcriptomics data through graph-based artificial intelligence

Q Song, J Su - Briefings in bioinformatics, 2021 - academic.oup.com
Recent development of spatial transcriptomics (ST) is capable of associating spatial
information at different spots in the tissue section with RNA abundance of cells within each …

Fusing higher and lower-order biological information for drug repositioning via graph representation learning

BW Zhao, L Wang, PW Hu, L Wong… - … on Emerging Topics …, 2023 - ieeexplore.ieee.org
Drug repositioning is a promising drug development technique to identify new indications for
existing drugs. However, existing computational models only make use of lower-order …

Multi-view multichannel attention graph convolutional network for miRNA–disease association prediction

X Tang, J Luo, C Shen, Z Lai - Briefings in Bioinformatics, 2021 - academic.oup.com
Motivation: In recent years, a growing number of studies have proved that microRNAs
(miRNAs) play significant roles in the development of human complex diseases. Discovering …

Aspect-level sentiment analysis: A survey of graph convolutional network methods

HT Phan, NT Nguyen, D Hwang - Information Fusion, 2023 - Elsevier
Aspect-level sentiment analysis (ALSA) is the process of collecting, processing, analyzing,
inferring, and synthesizing subjective sentiments of entities contained in texts at the aspect …