Medicinal herbs in the relief of neurological, cardiovascular, and respiratory symptoms after COVID-19 infection a literature review

J Nawrot, J Gornowicz-Porowska, J Budzianowski… - Cells, 2022 - mdpi.com
COVID-19 infection causes complications, even in people who have had a mild course of
the disease. The most dangerous seem to be neurological ailments: anxiety, depression …

Recent advances in the discovery of plant-derived antimicrobial natural products to combat antimicrobial resistant pathogens: insights from 2018–2022

S Woo, L Marquez, WJ Crandall, CJ Risener… - Natural Product …, 2023 - pubs.rsc.org
Covering: 2018 to 2022Antimicrobial resistance (AMR) poses a significant global health
threat. There is a rising demand for innovative drug scaffolds and new targets to combat …

Hypericin: A natural anthraquinone as promising therapeutic agent

JJ Wu, J Zhang, CY Xia, K Ding, XX Li, XG Pan, JK Xu… - Phytomedicine, 2023 - Elsevier
Background: Hypericin is a prominent secondary metabolite mainly existing in genus
Hypericum. It has become a research focus for a quiet long time owing to its extensively …

Strategies for the management of spike protein-related pathology

MTJ Halma, C Plothe, P Marik, TA Lawrie - Microorganisms, 2023 - mdpi.com
In the wake of the COVID-19 crisis, a need has arisen to prevent and treat two related
conditions, COVID-19 vaccine injury and long COVID-19, both of which can trace at least …

Hypericum perforatum L. and the Underlying Molecular Mechanisms for Its Choleretic, Cholagogue, and Regenerative Properties

A Mohagheghzadeh, P Badr, A Mohagheghzadeh… - Pharmaceuticals, 2023 - mdpi.com
Any defects in bile formation, secretion, or flow may give rise to cholestasis, liver fibrosis,
cirrhosis, and hepatocellular carcinoma. As the pathogenesis of hepatic disorders is …

In vivo and in vitro, antiviral effects of two mixture of Chinese herbal drug active monomers against MSRV and LMBV in largemouth bass (Micropterus salmoides)

Y Niu, X Fu, Q Lin, H Liang, X Luo, S Zuo, L Liu, N Li - Aquaculture, 2023 - Elsevier
Largemouth bass virus disease (LMBV) and Micropterus salmoides rhabdovirus (MSRV)
caused great economic losses to the fish industry. Currently, there are no effective drugs …

Multi-structural molecular docking (MOD) combined with molecular dynamics reveal the structural requirements of designing broad-spectrum inhibitors of SARS-CoV …

A Da, M Wu-Lu, J Dragelj, MA Mroginski… - Scientific Reports, 2023 - nature.com
New variants of SARS-CoV-2 that can escape immune response continue to emerge.
Consequently, there is an urgent demand to design small molecule therapeutics inhibiting …

Hypericin as a promising natural bioactive naphthodianthrone: A review of its pharmacology, pharmacokinetics, toxicity, and safety

Z Peng, J Lu, K Liu, L Xie, Y Wang, C Cai… - Phytotherapy …, 2023 - Wiley Online Library
Hypericin can be derived from St. John's wort, which is widely spread around the world. As a
natural product, it has been put into clinical practice such as wound healing and depression …

Surrogate Virus Neutralisation Test Based on Nanoluciferase-Tagged Antigens to Quantify Inhibitory Antibodies against SARS-CoV-2 and Characterise Omicron …

M Schoefbaenker, R Neddermeyer, T Guenther… - Vaccines, 2023 - mdpi.com
Virus-specific antibodies are crucial for protective immunity against SARS-CoV-2. Assessing
functional antibodies through conventional or pseudotyped virus neutralisation tests (pVNT) …

Production, Characterization, and In Vitro and In Vivo Studies of Nanoemulsions Containing St. John's Wort Plant Constituents and Their Potential for the Treatment of …

A Salawi, Y Almoshari, MH Sultan, OA Madkhali… - Pharmaceuticals, 2023 - mdpi.com
The current project was designed to prepare an oil-in-water (oil/water) hypericin
nanoemulsion using eucalyptus oil for the preparation of an oil phase with chitosan as an …