Mucormycosis

G Reid, JP Lynch III, MC Fishbein… - Seminars in respiratory …, 2020 - thieme-connect.com
Mucormycosis is an infection caused by a group of filamentous molds within the order
Mucorales. Infections may result from ingestion of contaminated food, inhalation of spores …

Antifungal drugs: what brings the future?

R Van Daele, I Spriet, J Wauters, J Maertens… - Medical …, 2019 - academic.oup.com
The high burden and growing prevalence of invasive fungal infections (IFIs), the toxicity and
interactions associated with current antifungal drugs, as well as the increasing resistance …

Invasive aspergillosis in solid‐organ transplant recipients: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

S Husain, JF Camargo - Clinical transplantation, 2019 - Wiley Online Library
These updated AST‐IDCOP guidelines provide information on epidemiology, diagnosis, and
management of Aspergillus after organ transplantation. Aspergillus is the most common …

Antifungal drugs TDM: trends and update

B Kably, M Launay, A Derobertmasure… - Therapeutic Drug …, 2022 - journals.lww.com
Purpose: The increasing burden of invasive fungal infections results in growing challenges
to antifungal (AF) therapeutic drug monitoring (TDM). This review aims to provide an …

Spotlight on isavuconazole in the treatment of invasive aspergillosis and mucormycosis: design, development, and place in therapy

JD Jenks, HJF Salzer, J Prattes, R Krause… - Drug design …, 2018 - Taylor & Francis
In recent decades, important advances have been made in the diagnosis and treatment of
invasive aspergillosis (IA) and mucormycosis. One of these advances has been the …

What is new in pulmonary mucormycosis?

F Danion, A Coste, C Le Hyaric, C Melenotte, F Lamoth… - Journal of Fungi, 2023 - mdpi.com
Mucormycosis is a rare but life-threatening fungal infection due to molds of the order
Mucorales. The incidence has been increasing over recent decades. Worldwide, pulmonary …

Isavuconazole concentration in real-world practice: consistency with results from clinical trials

D Andes, L Kovanda, A Desai, T Kitt… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Clinical use of voriconazole, posaconazole, and itraconazole revealed the need for
therapeutic drug monitoring (TDM) of plasma concentrations of these antifungal agents. This …

Isavuconazole prophylaxis in patients with hematologic malignancies and hematopoietic cell transplant recipients

L Fontana, DS Perlin, Y Zhao, BN Noble… - Clinical Infectious …, 2020 - academic.oup.com
Background Isavuconazole (ISA) is an attractive candidate for primary mold-active
prophylaxis in high-risk patients with hematologic malignancies or hematopoietic cell …

Population pharmacokinetics of isavuconazole in critical care patients with COVID-19-associated pulmonary aspergillosis and Monte Carlo simulations of high off …

L Perez, P Corne, G Pasquier, C Konecki, M Sadek… - Journal of Fungi, 2023 - mdpi.com
Isavuconazole is a triazole antifungal agent recently recommended as first-line therapy for
invasive pulmonary aspergillosis. With the COVID-19 pandemic, cases of COVID-19 …

Isavuconazole therapeutic drug monitoring in critically ill ICU patients: a monocentric retrospective analysis

R Höhl, R Bertram, M Kinzig, GS Haarmeyer… - Mycoses, 2022 - Wiley Online Library
Background The broad‐spectrum triazole isavuconazole is used for the treatment of invasive
aspergillosis and mucormycosis. Data regarding human plasma concentrations in clinical …