Beneficial properties of bromelain

P Hikisz, J Bernasinska-Slomczewska - Nutrients, 2021 - mdpi.com
Bromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants, having
multiple activities in many areas of medicine. Due to its low toxicity, high efficiency, high …

Bromelain and nisin: The natural antimicrobials with high potential in biomedicine

U Jančič, S Gorgieva - Pharmaceutics, 2021 - mdpi.com
Infectious diseases along with various cancer types are among the most significant public
health problems and the leading cause of death worldwide. The situation has become even …

Anticancer properties of bromelain: State-of-the-art and recent trends

R Pezzani, M Jimenez-Garcia, X Capo… - Frontiers in …, 2023 - frontiersin.org
Bromelain is a key enzyme found in pineapple (Ananas comosus (L.) Merr.); a proteolytic
substance with multiple beneficial effects for human health such as anti-inflammatory …

Microbial biotechnology approaches for conversion of pineapple waste in to emerging source of healthy food for sustainable environment

MK Awasthi, NIW Azelee, ANM Ramli… - International Journal of …, 2022 - Elsevier
One of the most significant and difficult jobs in food sustainability, is to make use of waste in
the vegetable and fruit processing sectors. The discarded fruits along with their waste …

Bromelain: from production to commercialisation

ANM Ramli, TNT Aznan, RM Illias - … of the Science of Food and …, 2017 - Wiley Online Library
Bromelain is a mixture of proteolytic enzymes found in pineapple (Ananas comosus) plants.
It can be found in several parts of the pineapple plant, including the stem, fruit, leaves and …

Secreted mucins in pseudomyxoma peritonei: pathophysiological significance and potential therapeutic prospects

A Amini, S Masoumi-Moghaddam, A Ehteda… - Orphanet journal of rare …, 2014 - Springer
Abstract Pseudomyxoma peritonei (PMP, ORPHA26790) is a clinical syndrome
characterized by progressive dissemination of mucinous tumors and mucinous ascites in the …

The chemopreventive action of bromelain, from pineapple stem (Ananas comosus L.), on colon carcinogenesis is related to antiproliferative and proapoptotic effects

B Romano, I Fasolino, E Pagano… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope Colorectal cancer is an important health problem across the world. Here, we
investigated the possible antiproliferative/proapoptotic effects of bromelain (from the …

A novel treatment of bromelain and acetylcysteine (BromAc) in patients with peritoneal mucinous tumours: A phase I first in man study

SJ Valle, J Akhter, AH Mekkawy, S Lodh, K Pillai… - European Journal of …, 2021 - Elsevier
Abstract Background Bromelain (Brom) and Acetylcysteine (Ac) have synergistic activity
resulting in dissolution of tumour-produced mucin both in vitro and in vivo. The aim of this …

Bromelain and N-acetylcysteine inhibit proliferation and survival of gastrointestinal cancer cells in vitro: significance of combination therapy

A Amini, S Masoumi-Moghaddam, A Ehteda… - Journal of Experimental …, 2014 - Springer
Background Bromelain and N-acetylcysteine are two natural, sulfhydryl-containing
compounds with good safety profiles which have been investigated for their benefits and …

Comparative study of antitumor effects of bromelain and papain in human cholangiocarcinoma cell lines

A Müller, S Barat, X Chen, KC Bui… - International …, 2016 - spandidos-publications.com
Cholangiocarcinoma (CC) worldwide is the most common biliary malignancy with poor
prognostic value and new systemic treatments are desirable. Plant extracts like bromelain …