Targeting epigenetic regulators to overcome drug resistance in cancers

N Wang, T Ma, B Yu - Signal transduction and targeted therapy, 2023 - nature.com
Drug resistance is mainly responsible for cancer recurrence and poor prognosis. Epigenetic
regulation is a heritable change in gene expressions independent of nucleotide sequence …

Clinical application and detection techniques of liquid biopsy in gastric cancer

S Ma, M Zhou, Y Xu, X Gu, M Zou, G Abudushalamu… - Molecular Cancer, 2023 - Springer
Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

Patterns in cancer incidence among people younger than 50 years in the US, 2010 to 2019

B Koh, DJH Tan, CH Ng, CE Fu, WH Lim… - JAMA Network …, 2023 - jamanetwork.com
Importance Emerging data suggest that the incidence of early-onset cancers, defined as
cancers diagnosed in people younger than 50 years, is increasing, but updated data are …

Impact of risk factors on early cancer evolution

CE Weeden, W Hill, EL Lim, E Grönroos, C Swanton - Cell, 2023 - cell.com
Recent identification of oncogenic cells within healthy tissues and the prevalence of indolent
cancers found incidentally at autopsies reveal a greater complexity in tumor initiation than …

Early-onset cancer in the gastrointestinal tract is on the rise—evidence and implications

I Ben-Aharon, HWM van Laarhoven, E Fontana… - Cancer discovery, 2023 - AACR
Epidemiologic data indicate a significant increase in the incidence of colorectal cancer in
younger populations in the past three decades. Moreover, recent evidence also …

The global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019

J Zhao, L Xu, J Sun, M Song, L Wang, S Yuan… - BMJ …, 2023 - research.ed.ac.uk
Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to
2019 Page 1 Edinburgh Research Explorer The Global Trends in Incidence, Death, Burden and …

Computational pathology in cancer diagnosis, prognosis, and prediction–present day and prospects

G Verghese, JK Lennerz, D Ruta, W Ng… - The Journal of …, 2023 - Wiley Online Library
Computational pathology refers to applying deep learning techniques and algorithms to
analyse and interpret histopathology images. Advances in artificial intelligence (AI) have led …

Changing epidemiology of colorectal cancer—birth cohort effects and emerging risk factors

CC Murphy, TA Zaki - Nature reviews Gastroenterology & hepatology, 2024 - nature.com
Incidence and mortality of colorectal cancer (CRC) are increasing worldwide, suggesting
broad changes in the epidemiology of CRC. In this Review, we discuss the changes that are …

Incidence and mortality of thyroid cancer in 50 countries: a joinpoint regression analysis of global trends

J Huang, CH Ngai, Y Deng, CN Pun, V Lok, L Zhang… - Endocrine, 2023 - Springer
Purpose To evaluate the incidence and mortality trend of thyroid cancer, and compare its
global incidence trends among different countries by age group and sex. Methods Data on …

Cancer profiles in China and comparisons with the USA: a comprehensive analysis in the incidence, mortality, survival, staging, and attribution to risk factors

S He, C Xia, H Li, M Cao, F Yang, X Yan… - Science China Life …, 2024 - Springer
China faces a disproportionate cancer burden to the population size and is undergoing a
transition in the cancer spectrum. We extracted data in five aspects of cancer incidence …