Background and Purpose This study investigated the contribution of white-matter
hyperintensities (WMH) and lacunar infarcts (LI) to the risk of Alzheimer's disease (AD) in an …

Introduction It is unknown whether different types of small vessel disease (SVD),
differentially relate to brain atrophy and if co‐occurring Alzheimer's disease pathology …

Background White matter abnormalities are a common feature of aging and Alzheimer
disease, and tend to be more severe among Black individuals. However, the extent to which …

Objective This study investigated cerebral small vessel disease (CSVD) damage patterns in
early‐onset and late‐onset Alzheimer's disease (EOAD and LOAD) and their effects on …

In older adults without dementia, White Matter Hyperintensities (WMH) in MRI have been
shown to be highly associated with cerebral amyloid deposition, measured by the Pittsburgh …

Background Neuropsychiatric symptoms associate cross-sectionally with cerebral small
vessel disease but it is not clear whether these symptoms could act as early clinical markers …

Background and Purpose We investigated the prevalence of amyloid positivity and cerebral
microbleeds (CMBs) in subjects with cognitive complaints with the aim of identifying …

Background: Idiopathic normal pressure hydrocephalus (iNPH) is often misdiagnosed as
Alzheimer's disease (AD) due to overlapping pathophysiology and similar imaging …

Abstract Background The NIA-AA proposed amyloid-tau-neurodegeneration (ATN) as a
classification system for AD biomarkers. The amyloid cascade hypothesis (ACH) implies a …

Hypertensive white matter lesion (WML) is one of common causes of vascular cognitive
impairment. In this study, we aimed to investigate the effect of rosuvastatin on cognitive …