[HTML][HTML] Fertility awareness-based methods for women's health and family planning
M Duane, JB Stanford, CA Porucznik, P Vigil - Frontiers in Medicine, 2022 - frontiersin.org
Background Fertility awareness-based methods (FABMs) educate about reproductive health
and enable tracking and interpretation of physical signs, such as cervical fluid secretions …
and enable tracking and interpretation of physical signs, such as cervical fluid secretions …
Simulating cancer growth with multiscale agent-based modeling
There have been many techniques developed in recent years to in silico model a variety of
cancer behaviors. Agent-based modeling is a specific discrete-based hybrid modeling …
cancer behaviors. Agent-based modeling is a specific discrete-based hybrid modeling …
[HTML][HTML] A mathematical model to predict nanomedicine pharmacokinetics and tumor delivery
Towards clinical translation of cancer nanomedicine, it is important to systematically
investigate the various parameters related to nanoparticle (NP) physicochemical properties …
investigate the various parameters related to nanoparticle (NP) physicochemical properties …
Innate immunity plays a key role in controlling viral load in COVID-19: mechanistic insights from a whole-body infection dynamics model
P Dogra, J Ruiz-Ramírez, K Sinha… - ACS pharmacology & …, 2020 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a pathogen of immense
public health concern. Efforts to control the disease have only proven mildly successful, and …
public health concern. Efforts to control the disease have only proven mildly successful, and …
Mathematical modeling in cancer drug discovery
Z Wang, TS Deisboeck - Drug discovery today, 2014 - Elsevier
Highlights•Mathematical models can help discover new drug targets for cancer.•Network-
based modeling can reveal promising single or combinatorial drug targets.•Multiscale …
based modeling can reveal promising single or combinatorial drug targets.•Multiscale …
Integrated PK-PD and agent-based modeling in oncology
Mathematical modeling has become a valuable tool that strives to complement conventional
biomedical research modalities in order to predict experimental outcome, generate new …
biomedical research modalities in order to predict experimental outcome, generate new …
[图书][B] An introduction to physical oncology: How mechanistic mathematical modeling can improve cancer therapy outcomes
Physical oncology has the potential to revolutionize cancer research and treatment. The
fundamental rationale behind this approach is that physical processes, such as transport …
fundamental rationale behind this approach is that physical processes, such as transport …
[HTML][HTML] Integration of transcriptomics data into agent-based models of solid tumor metastasis
Recent progress in our understanding of cancer mostly relies on the systematic profiling of
patient samples with high-throughput techniques like transcriptomics. With this approach …
patient samples with high-throughput techniques like transcriptomics. With this approach …
Mechanistic modeling-guided optimization of microneedle-based skin patch for rapid transdermal delivery of naloxone for opioid overdose treatment
Naloxone, an FDA-approved opioid inhibitor, used to reverse opioid overdose complications
has up till date faced challenges associated with its delivery. Limitations include the use of …
has up till date faced challenges associated with its delivery. Limitations include the use of …
[HTML][HTML] Translational modeling identifies synergy between nanoparticle-delivered miRNA-22 and standard-of-care drugs in triple-negative breast cancer
Purpose Downregulation of miRNA-22 in triple-negative breast cancer (TNBC) is associated
with upregulation of eukaryotic elongation 2 factor kinase (eEF2K) protein, which regulates …
with upregulation of eukaryotic elongation 2 factor kinase (eEF2K) protein, which regulates …