Antibiotic resistance is rapidly spreading among bacteria such as Staphylococcus aureus,
an opportunistic bacterial pathogen that causes a variety of diseases in humans. For the last …

The emergence of infections caused by multi-or pan-resistant bacteria in the hospital or in
the community settings is an increasing health concern. Albeit there is no single resistance …

NorA is the best studied efflux system of Staphylococcus aureus and therefore frequently
used as a model for investigating efflux-mediated resistance in this pathogen. NorA activity …

Increased expression of multidrug resistance efflux pump (MDR-EP) genes in clinical
isolates of Staphylococcus aureus occurs frequently, but its temporal and geographic …

Staphylococcus aureus is a notorious pathogen posing challenges in the medical industry
due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus …

NorA is one of the main native MDR efflux pumps of Staphylococcus aureus, contributing to
reduced susceptibility towards fluoroquinolones and biocides, but little is known about its …

Human beings interact with almost all kinds of living beings. The interaction is complexed by
the influence of environmental factors. These interactions assume various relationships …

Fluoroquinolone antibiotics have been a mainstay in the treatment of bacterial diseases. The
most notable representative, ciprofloxacin, possesses potent antimicrobial activity; however …

The biological membrane covers all living cells and provides an effective barrier against the
passage of biologically important water-soluble solutes. This natural passage barrier is …

The staphylococcal chromosome cassette mec cannot solely explain the multiresistance
phenotype or the relatively mild virulence profile of hospital-acquired methicillin-resistant …