Multiple studies suggested using different miRNAs as biomarkers for prognosis of
hepatocellular carcinoma (HCC). We aimed to assemble a miRNA expression database …

The hallmarks of cancer capture the most essential phenotypic characteristics of malignant
transformation and progression. Although numerous factors involved in this multi-step …

Prognostic biomarkers are of great significance to predict the outcome of patients with
cancer, to guide the clinical treatments, to elucidate tumorigenesis mechanisms, and offer …

The global burden of breast cancer (BC) is increasing significantly. This trend is caused by
several factors such as late diagnosis, limited treatment options for certain BC subtypes …

Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted
glycoprotein SFRP family. SFRP1 has been classified as a tumor suppressor gene due to …

Breast cancer is the most common cancer in women worldwide and is a substantial public
health problem. Screening for breast cancer mainly relies on mammography, which leads to …

Background Adrenocortical carcinoma is rare and aggressive endocrine cancer of the
adrenal gland. Within adrenocortical carcinoma, a recently described subtype characterized …

Before squamous cell lung cancer develops, precancerous lesions can be found in the
airways. From longitudinal monitoring, we know that only half of such lesions become …

Breast cancer susceptibility gene 1 (BRCA1) located at chromosome 17q12-21 is a classic
tumor suppressor gene and has been considered as a significant role in hereditary breast …

Introduction: Abnormal status of gene expression plays an important role in tumorigenesis,
progression and metastasis of breast cancer. Mechanisms of gene silence or activation were …