Saliva is a complex fluid produced by 3 pairs of major salivary glands and by hundreds of
minor salivary glands. It comprises a large variety of constituents and physicochemical …

We present here the hypothesis that the unique microenvironmental pH landscape of acid‐
base transporting epithelia is an important factor in development of epithelial cancers, by …

The mammalian pancreas is a branched organ that does not exhibit stereotypic branching
patterns, similarly to most other glands. Inside branches, it contains a network of ducts that …

Pancreatic duct cells are equipped with acid/base transporters important for exocrine
secretion. Pancreatic ductal adenocarcinoma (PDAC) cells may utilize such transporters to …

Background The human pancreatic cancer cell line A818–6 can be grown in vitro either as a
highly malignant, undifferentiated monolayer (ML) or as three-dimensional (3D) single layer …

Extracellular adenosine triphosphate (ATP) regulates pancreatic duct function via P2Y and
P2X receptors. It is well known that ATP is released from upstream pancreatic acinar cells …

The altered expression and/or activity of ion channels and transporters (transportome) have
been associated with malignant behavior of cancer cells and were proposed to be a …

We measured concentration changes of sodium, potassium, chloride ions, pH and the
transepithelial potential difference by means of ion-selective electrodes, which were placed …

Previous studies have shown that localized delivery of the aquaporin-1 (AQP1) gene to the
parotid duct can restore saliva flow in minipigs following irradiation-induced salivary …

This study was done to describe distribution of endocrine and exocrine pancreatic cells in
water buffalo. Hence, a total of 25 fresh pancreas samples were collected from slaughtered …