NRF2 (Nuclear factor E2 p45‐related factor 2) is a stress responsive transcription factor
lending cells resilience against oxidative, xenobiotic, and also nutrient or proteotoxic insults …

Acetaminophen (APAP) is a widely used analgesic and antipyretic drug, which is safe at
therapeutic doses but can cause severe liver injury and even liver failure after overdoses …

Aims Depression is one of the common neurological comorbidities in patients with
inflammatory bowel disease (IBD). The current study aimed to investigate the potential …

Ferulic acid, a bacterial metabolite of anthocyanins, seems likely to be a primary mediator of
the health benefits associated with anthocyanin-rich diets, and has long been employed in …

Ethnopharmacological relevance The seeds of Herpetospermum pedunculosum seeds is a
traditional Tibetan medicine possessing hepatoprotective effect, but their protective effect on …

Endemic arsenic (As) poisoning is a severe biogeochemical disease that endangers human
health. Epidemiological investigations and animal experiments have confirmed the …

Acetaminophen (APAP) is the most commonly used over-the-counter medication throughout
the world. At therapeutic doses, APAP has potent analgesic and antipyretic effects. The …

Although nicotinic acid (NA) has several clinical benefits, its potency cannot be fully utilized
due to several undesirable side effects, including cutaneous flushing, GIT-associated …

The aim of this study was to investigate the protective effect of nicotinamide adenine
dinucleotide (NAD+) against acute liver injury (ALI) induced by acetaminophen (APAP) …

Introduction: Administration of high doses of acetaminophen (APAP) results in liver injury.
Oxidative stress and iron overload play roles in the pathogenesis of APAP-induced …