Natural polymers, like chitosan and alginate have potential of appearance, as well as the
changes and handling necessary to make it acceptable vehicle for the controlled release of …

Pancreatic β-cell loss and failure with subsequent deficiency of insulin production is the
hallmark of type 1 diabetes (T1D) and late-stage type 2 diabetes (T2D). Despite the …

Deoxycholic acid (DCA), lithocholic acid (LCA), and ursodeoxycholic acid (UDCA) are bile
acids that may serve as permeation enhancers when incorporated within the nanogel matrix …

The biocompatibility and effects on cells' bioactivity of developed pharmaceuticals are
crucial properties, required to permit their safe delivery. Nanogel matrices offer a promising …

Deoxycholic acid (DCA) is a bile acid capable of forming micelles and modifying the
properties of hydrogels. We incorporated DCA in sodium alginate (SA) and poloxamer 407 …

Aim: Excessive free radicals contribute to oxidative stress and mitochondrial dysfunction in
sensorineural hearing loss (SNHL). The antioxidant probucol holds promise, but its limited …

Biguanides, particularly the widely prescribed drug metformin, have been marketed for many
decades and have well-established absorption profiles. They are commonly administered …

Introduction. Primary bile acids (PBAs) are produced and released into human gut as a
result of cholesterol catabolism in the liver. A predominant PBA is chenodeoxycholic acid …

Bile acids (BA) s are known surfactants and well-documented to play a major role in food
digestion and absorption. Recently, potential endocrinological and formulation-stabilisation …

Inner ear delivery requires safe and effective drug delivery vehicles incorporating high‐
viscosity formulations with permeation enhancers. This study designs novel …