[HTML][HTML] Maraviroc prevents HCC development by suppressing macrophages and the liver progenitor cell response in a murine chronic liver disease model

AM Passman, RP Strauss, SB McSpadden… - Cancers, 2021 - mdpi.com
Simple Summary Liver stem cells and activated macrophages have been implicated as
contributors to liver cancer; hence, reducing their abundance is a potential avenue for …

[HTML][HTML] Immune-stimulatory effects of curcumin on the tumor microenvironment in head and neck squamous cell carcinoma

C Kötting, L Hofmann, R Lotfi, D Engelhardt, S Laban… - Cancers, 2021 - mdpi.com
Simple Summary Head and neck squamous cell carcinoma has been shown to
downregulate the host's antitumor immune response as well as inherent anticancer …

Radiation therapy and the innate immune response: Clinical implications for immunotherapy approaches

V Gómez, R Mustapha, K Ng… - British journal of clinical …, 2020 - Wiley Online Library
Radiation therapy is an essential component of cancer care, contributing up to 40% of
curative cancer treatment regimens. It creates DNA double‐strand breaks causing cell death …

[HTML][HTML] The thyroid tumor microenvironment: potential targets for therapeutic intervention and prognostication

L MacDonald, J Jenkins, G Purvis, J Lee… - Hormones and Cancer, 2020 - Springer
Thyroid cancer is the most common endocrine malignancy and incidences are rising rapidly,
in both pediatric and adult populations. Many thyroid tumors are successfully treated which …

[HTML][HTML] Research progress on the role of tumor-associated macrophages in tumor development and their use as molecular targets

C Lu, Y Liu, L Miao, X Kong, H Li… - International …, 2023 - spandidos-publications.com
The tumor microenvironment (TME) is a complex system composed mainly of tumor cells,
mesenchymal cells and immune cells. Macrophages, also known as tumor-associated …

[HTML][HTML] Human Monocytes Are Suitable Carriers for the Delivery of Oncolytic Herpes Simplex Virus Type 1 In Vitro and in a Chicken Embryo Chorioallantoic …

A Reale, L Krutzke, M Cadamuro, A Vitiello… - International Journal of …, 2023 - mdpi.com
Oncolytic viruses (OVs) are promising therapeutics for tumors with a poor prognosis. An OV
based on herpes simplex virus type 1 (oHSV-1), talimogene laherparepvec (T-VEC), has …

[HTML][HTML] Tumour microenvironment in pheochromocytoma and paraganglioma

S Martinelli, F Amore, L Canu, M Maggi… - Frontiers in …, 2023 - frontiersin.org
Pheochromocytomas and Paragangliomas (Pheo/PGL) are rare catecholamine-producing
tumours derived from adrenal medulla or from the extra-adrenal paraganglia respectively …

Immune contexture of cholangiocarcinoma

J Paillet, G Kroemer, JG Pol - Current Opinion in Gastroenterology, 2020 - journals.lww.com
Immune contexture of cholangiocarcinoma : Current Opinion in Gastroenterology Immune
contexture of cholangiocarcinoma : Current Opinion in Gastroenterology Log in or Register …

The role of tumor epithelial-mesenchymal transition and macrophage crosstalk in cancer progression

AM May, L Batoon, LK McCauley, ET Keller - Current osteoporosis reports, 2023 - Springer
Abstract Purpose of Review The purpose of this review is to summarize the recently
published findings regarding the role of epithelial to mesenchymal transition (EMT) in tumor …

[HTML][HTML] TREM2 is associated with advanced stages and inferior prognosis in oral squamous cell carcinoma

AK Struckmeier, A Radermacher, M Fehrenz… - Cancers, 2022 - mdpi.com
Simple Summary Triggering receptor expressed on myeloid cells 2 (TREM2) is an appealing
candidate for immunotherapy. However, results regarding its role in multiple cancers are …