Abstract Purpose of Review The purpose of this review is to summarize the recently
published findings regarding the role of epithelial to mesenchymal transition (EMT) in tumor …

Many mechanisms favor tumor immune-escape. Each tumor exploits preferably some of
them and the challenge is to understand which are the best targets in each tumor. This …

Background Poorly differentiated thyroid cancer (PDTC) is a rare, follicular cell-derived
neoplasm with an unfavorable prognosis. The oncocytic variant of PDTC may be associated …

Macrophages are immune cells in the TME that can not only inhibit angiogenesis,
extracellular matrix remodeling, cancer cell proliferation, and metastasis but also mediate …

The etiology of head and neck squamous cell carcinoma (HNSCC) involves multiple
carcinogens, such as alcohol, tobacco, and infection with human papillomavirus (HPV) …

Immunotherapy has emerged as a promising new treatment modality for head and neck
cancer, offering the potential for targeted and effective cancer management. Squamous cell …

Tumor-infiltrating monocytes can mature into Macrophages that support tumor survival or
that display antitumor properties. To explore mechanisms steering Macrophage maturation …

The majority of meningiomas are grade I, but some grade I tumours are clinically more
aggressive. Recent advances in the genetic study of meningiomas has allowed investigation …

The tumor microenvironment (TME) is a complex system composed mainly of tumor cells,
mesenchymal cells and immune cells. Macrophages, also known as tumor‑associated …

OSCC (oral squamous cell carcinoma) is currently one of the most formidable cancers
plagued by challenges like low overall survivability, lymph node associated metastasis, drug …