Reducing oxidative stress stands at the center of a prevention and control strategy for
mitigating cellular senescence and aging. Kidney disease is characterized by a premature …

Diabetes mellitus (DM) belongs to the category of socially significant diseases with epidemic
rates of increases in prevalence. Diabetic nephropathy (DN) is a specific kind of kidney …

Renal fibrosis (RF) is the common pathological manifestation of virtually all chronic kidney
diseases (CKD) and one of the major causes of end-stage renal disease (ESRD), but the …

Objectives Diabetic kidney disease (DKD) is a prevalent microvascular complication of
diabetes. Inhibiting the epithelial-mesenchymal transition (EMT) of proximal tubule epithelial …

Ferroptosis is an important pathological process in acute kidney injury (AKI) which could
lead to chronic kidney disease (CKD) and end-stage renal disease (ESRD). As an active …

Background Acute kidney injury (AKI) refers to a tricky clinical disease, known by its high
morbidity and mortality, with no real specific medicine for AKI. The carbonization product …

Background: As a part of natural disease progression, acute kidney injury (AKI) can develop
into chronic kidney disease via renal fibrosis and inflammation. LTBP4 (latent transforming …

Introduction The potential effects of selenium nanoparticles (SeNPs) administration on
arsenic exposure-mediated nephrotoxicity by alleviating fibrosis, inflammation, oxidative …

Rationale: Renal fibrosis, with no therapeutic approaches, is a common pathological feature
in various chronic kidney diseases (CKD). Tubular cell injury plays a pivotal role in renal …

Aim Chronic kidney disease (CKD) is accompanied by increased cardiovascular risk and
heart failure (HF). In rodents, 2, 8-dihydroxyadenine (DHA)-induced nephropathy is a …