Dietary isothiocyanates inhibit cancer progression by modulation of epigenome
Cell cycle, growth, survival and metabolism are tightly regulated together and failure in
cellular regulation leads to carcinogenesis. Several signaling pathways like the PI3K, WNT …
cellular regulation leads to carcinogenesis. Several signaling pathways like the PI3K, WNT …
[HTML][HTML] Natural bioactive compounds targeting histone deacetylases in human cancers: recent updates
Cancer is a complex pathology that causes a large number of deaths worldwide. Several
risk factors are involved in tumor transformation, including epigenetic factors. These factors …
risk factors are involved in tumor transformation, including epigenetic factors. These factors …
[HTML][HTML] Application of Polyphenols and Flavonoids in Oncological Therapy
S Roszkowski - Molecules, 2023 - mdpi.com
The use of naturally derived drugs in anti-cancer therapies has grown exponentially in
recent years. Among natural compounds, polyphenols have shown potential therapeutic …
recent years. Among natural compounds, polyphenols have shown potential therapeutic …
[HTML][HTML] Potential of Kalanchoe pinnata as a Cancer Treatment Adjuvant and an Epigenetic Regulator
ME Hernández-Caballero, JA Sierra-Ramírez… - Molecules, 2022 - mdpi.com
Cancer is a global public health problem that is related to different environmental and
lifestyle factors. Although the combination of screening, prevention, and treatment of cancer …
lifestyle factors. Although the combination of screening, prevention, and treatment of cancer …
[HTML][HTML] Targeting of non-apoptotic cancer cell death mechanisms by quercetin: Implications in cancer therapy
H Yang, S Xu, L Tang, J Gong, H Fang… - Frontiers in …, 2022 - frontiersin.org
The ultimate goal of cancer treatment is to kill cancer cells, based on the use of various
therapeutic agents, such as chemotherapy, radiotherapy, or targeted therapy drugs. Most …
therapeutic agents, such as chemotherapy, radiotherapy, or targeted therapy drugs. Most …
[HTML][HTML] DNA methylation and hydroxymethylation in cervical cancer: diagnosis, prognosis and treatment
H Zhu, H Zhu, M Tian, D Wang, J He, T Xu - Frontiers in Genetics, 2020 - frontiersin.org
Recent discoveries have led to the development of novel ideas and techniques that have
helped elucidate the correlation between epigenetics and tumor biology. Nowadays, the …
helped elucidate the correlation between epigenetics and tumor biology. Nowadays, the …
[HTML][HTML] Flavonoids as epigenetic modulators for prostate cancer prevention
S Izzo, V Naponelli, S Bettuzzi - Nutrients, 2020 - mdpi.com
Prostate cancer (PCa) is a multifactorial disease with an unclear etiology. Due to its high
prevalence, long latency, and slow progression, PCa is an ideal target for chemoprevention …
prevalence, long latency, and slow progression, PCa is an ideal target for chemoprevention …
Polyphenols as adjunctive treatments in psychiatric and neurodegenerative disorders: Efficacy, mechanisms of action, and factors influencing inter-individual …
The pathophysiology of psychiatric and neurodegenerative disorders is complex and
multifactorial. Polyphenols possess a range of potentially beneficial mechanisms of action …
multifactorial. Polyphenols possess a range of potentially beneficial mechanisms of action …
[HTML][HTML] Metabolo-epigenetic interplay provides targeted nutritional interventions in chronic diseases and ageing
M Gómez de Cedrón, R Moreno Palomares… - Frontiers in …, 2023 - frontiersin.org
Epigenetic modifications are chemical modifications that affect gene expression without
altering DNA sequences. In particular, epigenetic chemical modifications can occur on …
altering DNA sequences. In particular, epigenetic chemical modifications can occur on …
Biocompatibility, cytotoxicity, antimicrobial and epigenetic effects of novel chitosan-based quercetin nanohydrogel in human cancer cells
S Abbaszadeh, M Rashidipour, P Khosravi… - International Journal …, 2020 - Taylor & Francis
Background Previous studies have reported that quercetin (Q) has a potential antibacterial
and anticancer activity. However, its application is limited by many important factors …
and anticancer activity. However, its application is limited by many important factors …