Skin cancer is a global threat to the healthcare system and is estimated to incline
tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is …

Obesity is a chronic inflammatory condition that has been associated with different types of
cancer. However, its role in melanoma incidence, progression, and response to immune …

Background Primary analysis of the phase 3 IMspire150 study showed improved
investigator-assessed progression-free survival with first-line atezolizumab, vemurafenib …

Despite advances in cancer treatment, immune checkpoint blockade (ICB) only achieves
complete response in some patients, illustrating the need to identify resistance mechanisms …

Therapeutic options for treating advanced melanoma have progressed rapidly in recent
decades. Until 6 years ago, the regimen for treating advanced melanoma consisted mainly …

Colorectal cancer (CRC) is among the most prevalent and deadly neoplasms worldwide.
According to GLOBOCAN predictions, its incidence will increase from 1.15 million CRC …

The early stages of melanoma could be treated promisingly by surgical resection; however,
the challenge is in advanced cases in which targeted therapy could be an option. The …

Melanoma, an aggressive form of skin cancer, can be fatal if not diagnosed and treated
early. Melanoma is widely recognized to resist advanced cancer treatments, including …

Checkpoint inhibitors are monoclonal antibodies that elicit an anti-tumor response by
stimulating immune system. Their use has improved the treatment of different types of cancer …

Simple Summary Immune checkpoint inhibitors are increasingly being used in the treatment
of a variety of cancers, both alone and in combination with other cancer therapies. Side …