The endoplasmic reticulum (ER) plays a vital function in maintaining cellular homeostasis.
Endoplasmic reticulum stress (ERS) can trigger various modes of cell death by activating the …

Sepsis, a life-threatening dysregulated status of the host response to infection, can cause
multiorgan dysfunction and mortality. Sepsis places a heavy burden on the cardiovascular …

Background: Tanshinone IIA, derived from Radix Salviae Miltiorrhizae (Salvia miltiorrhiza
Bunge), constitutes a significant component of this traditional Chinese medicine. Numerous …

At least seven cell death programs are activated during myocardial infarction (MI), but which
are most important in causing heart damage is not understood. Two of these programs are …

Patients undergoing doxorubicin (Dox) chemotherapy often develop new‐onset atrial
fibrillation and heart failure. Recent studies indicate that the TLR4/MyD88/NLRP3 pyroptosis …

Epicardial adipose tissue (EAT) is a metabolically active organ which generates
inflammatory cytokines. Thickness of EAT is associated with onset and development of heart …

Programmed cell death (PCD) is regarded as a pathological form of cell death with an
intracellular program mediated, which plays a pivotal role in maintaining homeostasis and …

Purpose Cardiovascular disease is commonly accompanied by renal dysfunction.
Multimorbidity in hospitalized patients impacts unfavorably on prognosis and hospital stay …

Background Cervical cancer, a pernicious gynecological malignancy, causes the mortality of
hundreds of thousands of females worldwide. Despite a considerable decline in mortality …

Pyroptosis is an inflammation-dependent type of cell death that has been in the spotlight for
the scientific community in the last few years. Crucial players in the process of pyroptosis are …