Salivary Biomarkers for Parkinson's Disease: A Systematic Review with Meta-Analysis
K Nijakowski, W Owecki, J Jankowski, A Surdacka - Cells, 2024 - mdpi.com
Parkinson's Disease (PD) is a common neurodegenerative disease which manifests with
motor features, such as bradykinesia, resting tremor, rigidity, and postural instability. Using …
motor features, such as bradykinesia, resting tremor, rigidity, and postural instability. Using …
Biomarkers of Parkinson's disease in perspective of early diagnosis and translation of neurotrophic therapies
RK Tuominen, JM Renko - Basic & Clinical Pharmacology & …, 2024 - Wiley Online Library
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by
progressive loss of dopamine neurons and aberrant deposits of alpha‐synuclein (α‐syn) in …
progressive loss of dopamine neurons and aberrant deposits of alpha‐synuclein (α‐syn) in …
Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers
J Nielsen, J Lauritsen, JN Pedersen, JS Nowak… - npj Parkinson's …, 2024 - nature.com
Abstract α-Synuclein (α-syn) accumulates as insoluble amyloid but also forms soluble α-syn
oligomers (αSOs), thought to be even more cytotoxic than fibrils. To detect and block the …
oligomers (αSOs), thought to be even more cytotoxic than fibrils. To detect and block the …
How close are we to a breakthrough? The hunt for blood biomarkers in Parkinson's disease diagnosis
C Liu, Y Su, X Ma, Y Wei, R Qiao - European Journal of …, 2024 - Wiley Online Library
Abstract Parkinson's disease (PD), being the second largest neurodegenerative disease,
poses challenges in early detection, resulting in a lack of timely treatment options to …
poses challenges in early detection, resulting in a lack of timely treatment options to …
Alpha-synuclein shapes monocyte and macrophage cell biology and functions by bridging alterations of autophagy and inflammatory pathways
F Limanaqi, S Zecchini, P Ogno, V Artusa… - Frontiers in Cell and …, 2024 - frontiersin.org
Introduction: Abnormal spreading of alpha-synuclein (αS), a hallmark of Parkinson's
disease, is known to promote peripheral inflammation, which occurs in part via functional …
disease, is known to promote peripheral inflammation, which occurs in part via functional …
[HTML][HTML] Unveiling defects of secretion mechanisms in Parkinson's disease
F Filippini, T Galli - Journal of Biological Chemistry, 2024 - Elsevier
Neurodegenerative diseases are characterized by progressive dysfunction and loss of
specific sets of neurons. While extensive research has focused on elucidating the genetic …
specific sets of neurons. While extensive research has focused on elucidating the genetic …
Decreased levels of phosphorylated synuclein in plasma are correlated with poststroke cognitive impairment
Y Wang, Y Li, Y Gu, W Ma, Y Guan, M Guo… - Neural Regeneration …, 2025 - journals.lww.com
Poststroke cognitive impairment is a major secondary effect of ischemic stroke in many
patients; however, few options are available for the early diagnosis and treatment of this …
patients; however, few options are available for the early diagnosis and treatment of this …
Fluid and tissue biomarkers in Parkinson's disease: Immunodetection or seed amplification? Central or peripheral?
C Painous, M Fernández, J Pérez, L de Mena… - Parkinsonism & Related …, 2023 - Elsevier
Over the last two decades there have been meaningful developments on biomarkers of
neurodegenerative diseases, extensively (but not solely) focusing on their proteinopathic …
neurodegenerative diseases, extensively (but not solely) focusing on their proteinopathic …
[PDF][PDF] Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies
DS Prudinnik, A Kussanova, IA Vorobjev… - Aging and …, 2025 - researchgate.net
Aging is interrelated with changes in red blood cell parameters and functionality. In this
article, we focus on red blood cells (RBCs) and provide a review of the known changes …
article, we focus on red blood cells (RBCs) and provide a review of the known changes …
Biomarkers of Parkinson's disease in perspective of early diagnosis and translation of neurotrophic therapies
JM Renko, R Tuominen - Authorea Preprints, 2023 - techrxiv.org
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by
progressive loss of dopamine neurons and aberrant deposits of alpha-synuclein (a-syn) in …
progressive loss of dopamine neurons and aberrant deposits of alpha-synuclein (a-syn) in …