Targeting autophagy using natural compounds for cancer prevention and therapy
S Deng, MK Shanmugam, AP Kumar, CT Yap, G Sethi… - Cancer, 2019 - Wiley Online Library
Autophagy, also known as macroautophagy, is a tightly regulated process involved in the
stress responses, such as starvation. It is a vacuolar, lysosomal pathway for the degradation …
stress responses, such as starvation. It is a vacuolar, lysosomal pathway for the degradation …
Potential therapeutic targets of resveratrol, a plant polyphenol, and its role in the therapy of various types of cancer
Cancer is among the most prominent causes of mortality worldwide. Different cancer therapy
modes employed, including chemotherapy and radiotherapy, have been reported to be …
modes employed, including chemotherapy and radiotherapy, have been reported to be …
Modulation of autophagy in cancer cells by dietary polyphenols
C Musial, K Siedlecka-Kroplewska, Z Kmiec… - Antioxidants, 2021 - mdpi.com
The role of autophagy is to degrade damaged or unnecessary cellular structures. Both in
vivo and in vitro studies suggest a dual role of autophagy in cancer—it may promote the …
vivo and in vitro studies suggest a dual role of autophagy in cancer—it may promote the …
Molecular insights into the multifunctional role of natural compounds: autophagy modulation and cancer prevention
Autophagy is a vacuolar, lysosomal degradation pathway for injured and damaged protein
molecules and organelles in eukaryotic cells, which is controlled by nutrients and stress …
molecules and organelles in eukaryotic cells, which is controlled by nutrients and stress …
Polyphenols and their metabolites in renal diseases: An overview
Kidney diseases constitute a worldwide public health problem, contributing to morbidity and
mortality. The present study aimed to provide an overview of the published data regarding …
mortality. The present study aimed to provide an overview of the published data regarding …
Resveratrol as an enhancer of apoptosis in cancer: a mechanistic review
M Ashrafizadeh, S Taeb… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
The resistance to therapy of cancer cells is a challenge for achieving an appropriate
therapeutic outcome. Cancer (stem) cells possess several mechanisms for increasing their …
therapeutic outcome. Cancer (stem) cells possess several mechanisms for increasing their …
Plant-derived medicines for treatment of endometriosis: A comprehensive review of molecular mechanisms
Endometriosis is an estrogen-dependent disease with inflammatory lesions at extra-uterine
sites, causing pelvic pain and fertility reduction. Conventional therapies primarily focus on …
sites, causing pelvic pain and fertility reduction. Conventional therapies primarily focus on …
Novel approaches of dysregulating lysosome functions in cancer cells by specific drugs and its nanoformulations: a smart approach of modern therapeutics
The smart strategy of cancer cells to bypass the caspase-dependent apoptotic pathway has
led to the discovery of novel anti-cancer approaches including the targeting of lysosomes …
led to the discovery of novel anti-cancer approaches including the targeting of lysosomes …
Phytochemicals for the prevention and treatment of renal cell carcinoma: preclinical and clinical evidence and molecular mechanisms
EM Bajalia, FB Azzouz, DA Chism, DM Giansiracusa… - Cancers, 2022 - mdpi.com
Simple Summary Renal cell carcinoma (RCC) is the most frequently diagnosed kidney
cancer. Once RCC metastasizes, successful treatment is difficult to achieve. There is an …
cancer. Once RCC metastasizes, successful treatment is difficult to achieve. There is an …
Resveratrol induces apoptosis and attenuates proliferation of MCF-7 cells in combination with radiation and hyperthermia
P Amini, SJ Nodooshan, M Ashrafizadeh… - Current molecular …, 2021 - ingentaconnect.com
Aim: In the current in vitro study, we tried to examine the possible role of resveratrol as a
sensitizer in combination with radiotherapy or hyperthermia. Background: Breast cancer is …
sensitizer in combination with radiotherapy or hyperthermia. Background: Breast cancer is …