Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: A systematic literature review

G Chappell, IP Pogribny, KZ Guyton, I Rusyn - Mutation Research/Reviews …, 2016 - Elsevier
Accumulating evidence suggests that epigenetic alterations play an important role in
chemically-induced carcinogenesis. Although the epigenome and genome may be equally …

Melatonin as modulator for sulfur and nitrogen mustard-induced inflammation, oxidative stress and DNA damage: Molecular therapeutics

E Ramos, E Gil-Martín, C De Los Ríos, J Egea… - Antioxidants, 2023 - mdpi.com
Sulfur and nitrogen mustards, bis (2-chloroethyl) sulfide and tertiary bis (2-chloroethyl)
amines, respectively, are vesicant warfare agents with alkylating activity. Moreover …

Overview of biological mechanisms of human carcinogens

N Birkett, M Al-Zoughool, M Bird, RA Baan… - Journal of Toxicology …, 2019 - Taylor & Francis
This review summarizes the carcinogenic mechanisms for 109 Group 1 human carcinogens
identified as causes of human cancer through Volume 106 of the IARC Monographs. The …

Increase of global DNA methylation patterns in beauty salon workers exposed to low levels of formaldehyde

E Barbosa, ALA Dos Santos, GP Peteffi… - … Science and Pollution …, 2019 - Springer
Formaldehyde (FA) is a carcinogenic aldehyde illegally added to creams as a hair
straightening agent for the Brazilian blowout (BB). This study aimed to investigate the …

Progress towards a standardized model of ocular sulfur mustard injury for therapeutic testing

P McNutt - Experimental eye research, 2023 - Elsevier
Sulfur mustard (SM) remains a highly dangerous chemical weapon capable of producing
mass casualties through liquid or vapor exposure. The cornea is highly sensitive to SM …

Sulfur mustard skin lesions: A systematic review on pathomechanisms, treatment options and future research directions

D Rose, A Schmidt, M Brandenburger, T Sturmheit… - Toxicology Letters, 2018 - Elsevier
Sulfur mustard (SM) is a chemical warfare, which has been used for one hundred years.
However, its exact pathomechanisms are still incompletely understood and there is no …

Toxicology of blister agents: is melatonin a potential therapeutic option?

A Romero, E Ramos, F López-Muñoz, C De Los Ríos… - Diseases, 2021 - mdpi.com
Blister or vesicant chemical warfare agents (CWAs) have been widely used in different
military conflicts, including World War I and the Iran-Iraq War. However, their mechanism of …

Advances in sulfur mustard-induced DNA adducts: Characterization and detection

X Cheng, C Liu, Y Yang, L Liang, B Chen, H Yu, J Xia… - Toxicology letters, 2021 - Elsevier
Sulfur mustard (SM) is a blister chemical warfare agent with severe cytotoxicity and
genotoxicity. It can extensively alkylate important macromolecules in organisms, such as …

Role of oxidative stress and antioxidant therapy in acute and chronic phases of sulfur mustard injuries: a review

A Beigi Harchegani, A Khor… - … and ocular toxicology, 2019 - Taylor & Francis
Sulfur mustard (SM) is a chemical compound that preferentially targets ocular, cutaneous
and pulmonary tissues. Although pathologic effect of SM has been extensively considered …

Emerging targets for treating sulfur mustard–induced injuries

S Ahmad, A Ahmad - Annals of the New York Academy of …, 2016 - Wiley Online Library
Sulfur mustard (SM; bis‐(2‐chlororethyl) sulfide) is a highly reactive, potent warfare agent
that has recently reemerged as a major threat to military and civilians. Exposure to SM is …