Antiviral potential of curcumin

D Mathew, WL Hsu - Journal of functional foods, 2018 - Elsevier
The use of synthetic drugs has increased over the recent years, but plant-based drugs are
more suitable in terms of least side effects. Since ancient times mankind has been …

Curcumin as a multifaceted compound against human papilloma virus infection and cervical cancers: A review of chemistry, cellular, molecular, and preclinical …

M Teymouri, M Pirro, TP Johnston, A Sahebkar - BioFactors, 2017 - Wiley Online Library
Curcumin, the bioactive polyphenolic ingredient of turmeric, has been extensively studied for
its effects on human papilloma virus (HPV) infection as well as primary and malignant …

Anti-viral potential and modulation of Nrf2 by curcumin: pharmacological implications

M Rahban, M Habibi-Rezaei, M Mazaheri, L Saso… - Antioxidants, 2020 - mdpi.com
Nuclear factor erythroid 2-related factor 2 (Nrf2) is an essential transcription factor that
maintains the cell's redox balance state and reduces inflammation in different adverse …

An overview of novel agents for cervical cancer treatment by inducing apoptosis: Emerging drugs ongoing clinical trials and preclinical studies

L Liu, M Wang, X Li, S Yin, B Wang - Frontiers in medicine, 2021 - frontiersin.org
As the leading cause of cancer death, cervical cancer ranks fourth for both incidence and
mortality. Cervical cancer incidence and mortality rates have reportedly decreased over the …

Curcumin analogues and derivatives with anti-proliferative and anti-inflammatory activity: Structural characteristics and molecular targets

E Chainoglou, D Hadjipavlou-Litina - Expert opinion on drug …, 2019 - Taylor & Francis
ABSTRACT Introduction: Curcumin (Diferuloylmethane) is a natural phenolic compound,
which belongs to the curcuminoid family, presenting pleiotropic activity and low …

Bringing curcumin to the clinic in cancer prevention: a review of strategies to enhance bioavailability and efficacy

RI Mahran, MM Hagras, D Sun, DE Brenner - The AAPS journal, 2017 - Springer
Curcumin is widely available, inexpensive spice that has been used in ancient folk medicine
for millennia, especially in India. Curcumin has the pharmacological properties that slow or …

Curcumin piperidone derivatives induce anti-proliferative and anti-migratory effects in LN-18 human glioblastoma cells

NSC Razali, KW Lam, NF Rajab, AR A. Jamal… - Scientific Reports, 2022 - nature.com
Curcumin has demonstrated potential cytotoxicity across various cell lines despite its poor
bioavailability and rapid metabolism. Therefore, our group have synthesized curcuminoid …

Curcumin-conjugated gold clusters for bioimaging and anticancer applications

S Govindaraju, A Rengaraj, R Arivazhagan… - Bioconjugate …, 2018 - ACS Publications
Curcumin-conjugated gold clusters (CUR-AuNCs) were synthesized using a “green”
procedure and utilized as an anticancer and a bioimaging agent. Curcumin is a well-known …

Diarylpentanoids with antitumor activity: A critical review of structure-activity relationship studies

J Moreira, L Saraiva, MM Pinto, H Cidade - European Journal of Medicinal …, 2020 - Elsevier
Diarypentanoids are commonly considered as monocarbonyl analogues of curcumin. Since
the discovery of this compound in 1962, twenty one diarylpentanoids have been isolated …

The curcumin analogue, MS13 (1, 5-Bis (4-hydroxy-3-methoxyphenyl)-1, 4-pentadiene-3-one), inhibits cell proliferation and induces apoptosis in primary and …

NI Ismail, I Othman, F Abas, N H. Lajis, R Naidu - Molecules, 2020 - mdpi.com
The cytotoxic and apoptotic effects of turmeric (Curcuma longa) on colon cancer have been
well documented but specific structural modifications of curcumin have been shown to …