In contrast to the decreasing incidence of colorectal cancer (CRC) in older populations, the
incidence has nearly doubled in younger adults since the early 1990s. Approximately 1 in …

Regarding the continuous changes in the diagnostic process and treatment of colorectal
cancer (CRC), it is important to evaluate long‐term trends which are relevant in giving …

Importance Resource limitations because of pandemic or other stresses on infrastructure
necessitate the triage of time-sensitive care, including cancer treatments. Optimal time to …

Background: The prognostic value of BRAF and KRAS mutations within microsatellite-
unstable (MSI) and microsatellite-stable (MSS) subgroups of resected colon carcinoma …

Purpose Colorectal cancer (CRC) treatment is largely determined by tumor stage. Despite
improvements made in the treatment of various types of metastatic disease, staging has not …

Purpose Fluorouracil plus leucovorin (FU+ LV) adjuvant chemotherapy reduced the risk of
recurrence and death across all time points in a pooled analysis of 20,898 patients with …

The colorectal cancer (CRC) patients with microsatellite instability (MSI) have distinct
clinicopathological characteristics consisting of factors predicting positive and negative …

Background: Among colorectal cancers (CRCs), high-frequency microsatellite instability
(MSI-H) is associated with a better prognosis, compared with low-frequency MSI or …

Background Emergency complications of colon cancer include perforation and obstruction
which were recognized as poor prognostic factors. Few studies have directly compared the …

Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease in developed
countries. Its frequency is increasing in the general population mostly due to the widespread …