Chemical aspects of human and environmental overload with fluorine

J Han, L Kiss, H Mei, AM Remete… - Chemical …, 2021 - ACS Publications
Over the last 100–120 years, due to the ever-increasing importance of fluorine-containing
compounds in modern technology and daily life, the explosive development of the …

Principles of fluoride toxicity and the cellular response: a review

NR Johnston, SA Strobel - Archives of toxicology, 2020 - Springer
Fluoride is ubiquitously present throughout the world. It is released from minerals, magmatic
gas, and industrial processing, and travels in the atmosphere and water. Exposure to low …

Taurine as a natural antioxidant: From direct antioxidant effects to protective action in various toxicological models

PF Surai, K Earle-Payne, MT Kidd - Antioxidants, 2021 - mdpi.com
Natural antioxidants have received tremendous attention over the last 3 decades. At the
same time, the attitude to free radicals is slowly changing, and their signalling role in …

Fluoride exposure induces mitochondrial damage and mitophagy via activation of the IL-17A pathway in hepatocytes

Y Zhao, J Wang, J Zhang, Z Sun, R Niu… - Science of the Total …, 2022 - Elsevier
As an environmental toxicant, the damage of fluoride to the body has attracted global
attention. Because liver is an essential organ for fluoride accumulation and damage. Our …

[HTML][HTML] A novel role of kallikrein-related peptidase 8 in the pathogenesis of diabetic cardiac fibrosis

JK Du, Q Yu, YJ Liu, SF Du, LY Huang, DH Xu, X Ni… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Among all the diabetic complications, diabetic cardiomyopathy, which is
characterized by myocyte loss and myocardial fibrosis, is the leading cause of mortality and …

Effects of fluoride exposure on mitochondrial function: energy metabolism, dynamics, biogenesis and mitophagy

SH Avila-Rojas, OE Aparicio-Trejo… - Environmental …, 2022 - Elsevier
Fluoride is ubiquitous in the environment. Furthermore, drinking water represents the main
source of exposure to fluoride for humans. Interestingly, low fluoride concentrations have …

[HTML][HTML] Molecular basis of fluoride toxicities: beyond benefits and implications in human disorders

P Pal, NK Jha, D Pal, SK Jha, U Anand… - Genes & …, 2023 - Elsevier
Detrimental impacts of fluoride have become a global concern for several decades. Despite
its beneficial role which is restricted only in skeletal tissues, deleterious effects are also …

Fluoride network and circular economy as potential model for sustainable development-A review

CFZ Lacson, MC Lu, YH Huang - Chemosphere, 2020 - Elsevier
Fluorine is the most reactive elements among the halogen group and commonly and
ubiquitously occurs as fluoride in nature. The industrial processes produce fluoride by …

Changes in energy metabolism induced by fluoride: Insights from inside the mitochondria

TT Araujo, HABS Pereira, A Dionizio… - Chemosphere, 2019 - Elsevier
The mechanisms involved in changes in energy metabolism caused by excessive exposure
to fluoride (F) are not completely understood. The present study employed proteomic tools to …

[HTML][HTML] Systematic impacts of fluoride exposure on the metabolomics of rats

S Zhao, J Guo, H Xue, J Meng, D Xie, X Liu… - Ecotoxicology and …, 2022 - Elsevier
Fluoride is widely present in the environment. Excessive fluoride exposure leads to fluorosis,
which has become a global public health problem and will cause damage to various organs …