Plasticity in animal behaviour relies on the ability to integrate external and internal cues from
the changing environment and hence modulate activity in synaptic circuits of the brain. This …

Proper regulation of ion balance across the intestinal epithelium is essential for
physiological functions, while ion imbalance causes intestinal disorders with dire health …

Animals must adapt their dietary choices to meet their nutritional needs. How these needs
are detected and translated into nutrient-specific appetites that drive food-choice behaviours …

Obesity imposes a global health threat and calls for safe and effective therapeutic options.
Here, we found that protein-rich diet significantly reduced body fat storage in fruit flies, which …

The intestine is a central regulator of metabolic homeostasis. Dietary inputs are absorbed
through the gut, which senses their nutritional value and relays hormonal information to …

Sex differences in whole-body fat storage exist in many species. For example, Drosophila
females store more fat than males. Yet, the mechanisms underlying this sex difference in fat …

Oogenesis is influenced by multiple environmental factors. In the fruit fly, Drosophila
melanogaster, nutrition and mating have large impacts on an increase in female germline …

Whole-body health relies on complex inter-organ signalling networks that enable organisms
to adapt to environmental perturbations and to changes in tissue homeostasis. The intestine …

Post-developmental organ resizing improves organismal fitness under constantly changing
nutrient environments. Although stem cell abundance is a fundamental determinant of …

BACKGROUND Feeding by pests is one of the most important reasons for reductions in
agricultural crop yield. This study aimed to reveal how juvenile hormone (JH) participates in …