Until the advent of immune checkpoint inhibitors (ICIs), definitive radiotherapy (RT)
concurrently with chemotherapy was recommended for unresectable, locally advanced non …

Soft tissue sarcoma (STS) is a highly heterogeneous malignant tumor derived from
mesenchymal tissue. Advanced STS has a poor response to the current anti-cancer …

Radiotherapy can act as an in situ vaccine, activating preventive tumor-specific immune
responses in patients. Although carbon ion radiotherapy has superior biophysical properties …

Seas and oceans have been explored for the last 70 years in search of new compounds that
can support the battle against cancer. Marine polysaccharides can act as nanomaterials for …

Background Radiation therapy combined with immune checkpoint inhibitors (ICIs) has
recently turned into an appealing and promising approach to enhance the anti-tumor …

Radiotherapy (RT) is a fundamental treatment at the locoregional or oligometastatic stages
of cancer. In various tumors, RT effects may be optimized using synergistic combinations …

Background: The abscopal effect, in which radiation induces a systemic anti-tumour immune
response, has been demonstrated with radiotherapy. Immunotherapy boosts the abscopal …

Background Although rectal cancer remains somewhat sanctuary to the contemporary
immunotherapy, there is increasing knowledge on clinical implications of anti-tumor …

Patients with chemo-refractory metastatic colorectal cancer (mCRC) have poor prognoses.
The application of programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 …

Microenvironmental conditions control the entrance and thriving of cytotoxic lymphocytes in
tumors, allowing or preventing immune-mediated cancer cell death. We investigated the role …