Background. We have previously reported a 10% incidence of posttransplant
lymphoproliferative disease (PTLD) in pediatric patients receiving first liver grafts and …

Zika fever, a mosquito-borne infectious disease caused by Zika virus (ZIKV), is an epidemic
disease for which no effective therapy has been established. The recent outbreaks of ZIKV in …

Varicella-zoster virus has developed a complex strategy that allows it to remain latent in the
body and avoid destruction by the immune system. Although varicella and zoster have been …

Antiviral therapy of primary and recurrent infections with human cytomegalovirus is reserved
for severe manifestations and faces several limitations. Presently candidates for novel drugs …

Background: Herpes zoster is a common affliction in older patients, with up to 15%
experiencing some residual pain in the distribution of the rash several months after healing …

In this study, baseline plasma from 619 persons with acquired immunodeficiency syndrome
(AIDS)(median CD4+ lymphocyte count-21/microl) who participated in a trial to determine …

Simple Summary Despite the leaps and bounds in the prevention and treatment of cancer, it
remains the second leading cause of death worldwide. A significant hurdle during cancer …

Continued but slow progress has led to recent advances in our understanding that
congenital cytomegalovirus (CMV) infection has occurred. We understand that the most …

Cytomegalovirus (CMV) replicates rapidly in its human host with a doubling time of≈ 1 day.
Using simple mathematical models we show that the efficacy of the anti-CMV drug …

The human cytomegalovirus UL97 kinase, an important target of antiviral therapy, has an
impact on at least two distinct phases of viral replication. Compared with wild-type virus, the …