[HTML][HTML] Horizontal gene transfer of antibiotic resistance genes in biofilms

C Michaelis, E Grohmann - Antibiotics, 2023 - mdpi.com
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …

[HTML][HTML] The spread of antibiotic resistance to humans and potential protection strategies

D Ding, B Wang, X Zhang, J Zhang, H Zhang… - Ecotoxicology and …, 2023 - Elsevier
Antibiotic resistance is currently one of the greatest threats to human health. Widespread
use and residues of antibiotics in humans, animals, and the environment can exert selective …

[HTML][HTML] Biofilms: Understanding the structure and contribution towards bacterial resistance in antibiotics

P Shree, CK Singh, KK Sodhi, JN Surya… - Medicine in …, 2023 - Elsevier
The biofilm is a bacterial colony wrapped in an auto-produced polymer matrix of
polysaccharides, proteins, and DNA. Bacterial biofilms cause persistent infections because …

[HTML][HTML] Leishmania parasites exchange drug-resistance genes through extracellular vesicles

N Douanne, G Dong, A Amin, L Bernardo, M Blanchette… - Cell reports, 2022 - cell.com
Leishmania are eukaryotic parasites that have retained the ability to produce extracellular
vesicles (EVs) through evolution. To date, it has been unclear if different DNA entities could …

[HTML][HTML] Evaluation of antibiotic resistance mechanisms in gram-negative bacteria

A Gauba, KM Rahman - Antibiotics, 2023 - mdpi.com
Multidrug-resistant Gram-negative bacterial infections are exponentially increasing, posing
one of the most urgent global healthcare and economic threats. Due to the lack of new …

[HTML][HTML] Outer Membrane Vesicles Derived from Klebsiella pneumoniae Are a Driving Force for Horizontal Gene Transfer

F Dell'Annunziata, C Dell'Aversana, N Doti… - International Journal of …, 2021 - mdpi.com
Gram-negative bacteria release Outer Membrane Vesicles (OMVs) into the extracellular
environment. Recent studies recognized these vesicles as vectors to horizontal gene …

[HTML][HTML] Fusobacterium nucleatum outer membrane vesicles activate autophagy to promote oral cancer metastasis

G Chen, C Gao, S Jiang, Q Cai, R Li, Q Sun… - Journal of Advanced …, 2024 - Elsevier
Introduction Metastasis is an important cause of high mortality and lethality of oral cancer.
Fusobacterium nucleatum (Fn) can promote tumour metastasis. Outer membrane vesicles …

The application of the CRISPR-Cas system in antibiotic resistance

S Tao, H Chen, N Li, W Liang - Infection and drug resistance, 2022 - Taylor & Francis
The emergence and global epidemic of antimicrobial resistance (AMR) poses a serious
threat to global public health in recent years. AMR genes are shared between bacterial …

[HTML][HTML] Augmented dissemination of antibiotic resistance elicited by non-antibiotic factors

S Zhu, B Yang, Z Wang, Y Liu - Ecotoxicology and Environmental Safety, 2023 - Elsevier
The emergence and rapid spread of antibiotic resistance seriously compromise the clinical
efficacy of current antibiotic therapies, representing a serious public health threat worldwide …

Bacterial membrane vesicles: physiological roles, infection immunology, and applications

Y Gan, G Zhao, Z Wang, X Zhang, MX Wu… - Advanced …, 2023 - Wiley Online Library
Bacterial or fungal membrane vesicles, traditionally considered as microbial metabolic
wastes, are secreted mainly from the outer membrane or cell membrane of microorganisms …