Using MetaboAnalyst 5.0 for LC–HRMS spectra processing, multi-omics integration and covariate adjustment of global metabolomics data
Liquid chromatography coupled with high-resolution mass spectrometry (LC–HRMS) has
become a workhorse in global metabolomics studies with growing applications across …
become a workhorse in global metabolomics studies with growing applications across …
Applications of multi-omics technologies for crop improvement
Y Yang, MA Saand, L Huang, WB Abdelaal… - Frontiers in Plant …, 2021 - frontiersin.org
Multiple “omics” approaches have emerged as successful technologies for plant systems
over the last few decades. Advances in next-generation sequencing (NGS) have paved a …
over the last few decades. Advances in next-generation sequencing (NGS) have paved a …
Small molecule metabolites: discovery of biomarkers and therapeutic targets
S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
Artificial intelligence-based multi-omics analysis fuels cancer precision medicine
With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …
emerging that have enabled researchers to access multi-layer information from the genome …
The potential of metabolomics in biomedical applications
V Gonzalez-Covarrubias, E Martínez-Martínez… - Metabolites, 2022 - mdpi.com
The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …
Current high-throughput technologies have allowed the discovery of relevant metabolites …
Identification and prioritization of environmental organic pollutants: from an analytical and toxicological perspective
Exposure to environmental organic pollutants has triggered significant ecological impacts
and adverse health outcomes, which have been received substantial and increasing …
and adverse health outcomes, which have been received substantial and increasing …
Metabolite annotation from knowns to unknowns through knowledge-guided multi-layer metabolic networking
Liquid chromatography-mass spectrometry (LC-MS) based untargeted metabolomics allows
to measure both known and unknown metabolites in the metabolome. However, unknown …
to measure both known and unknown metabolites in the metabolome. However, unknown …
Schiff base aggregation-induced emission luminogens for sensing applications: a review
J Wang, Q Meng, Y Yang, S Zhong, R Zhang… - ACS …, 2022 - ACS Publications
Fluorescence sensing can not only identify a target substrate qualitatively but also achieve
the purpose of quantitative detection through the change of the fluorescence signal. It has …
the purpose of quantitative detection through the change of the fluorescence signal. It has …
Prospects of surface-enhanced Raman spectroscopy for biomarker monitoring toward precision medicine
Future precision medicine will be undoubtedly sustained by the detection of validated
biomarkers that enable a precise classification of patients based on their predicted disease …
biomarkers that enable a precise classification of patients based on their predicted disease …
Emerging therapies in cancer metabolism
Y Xiao, TJ Yu, Y Xu, R Ding, YP Wang, YZ Jiang… - Cell Metabolism, 2023 - cell.com
Metabolic reprogramming in cancer is not only a biological hallmark but also reveals
treatment vulnerabilities. Numerous metabolic molecules have shown promise as treatment …
treatment vulnerabilities. Numerous metabolic molecules have shown promise as treatment …