Diagnosis of Parkinson's Disease via the Metabolic Fingerprint in Saliva by Deep Learning

W Xu, L Chen, G Cai, M Gao, Y Chen, J Pu… - Small …, 2023 - Wiley Online Library
Parkinson's disease (PD) is the second cause of the neurodegenerative disorder, affecting
over 6 million people worldwide. The World Health Organization estimated that population …

Best practices in NMR metabolomics: Current state

R Powers, ER Andersson, AL Bayless, RB Brua… - TrAC Trends in …, 2023 - Elsevier
A literature survey was conducted to identify current practices used by NMR metabolomics
investigators when conducting and reporting their metabolomics studies. A total of 463 …

Resource competition predicts assembly of gut bacterial communities in vitro

PY Ho, TH Nguyen, JM Sanchez, BC DeFelice… - Nature …, 2024 - nature.com
Microbial community dynamics arise through interspecies interactions, including resource
competition, cross-feeding and pH modulation. The individual contributions of these …

Natural variance at the interface of plant primary and specialized metabolism

S Wang, Y Li, L He, J Yang, AR Fernie, J Luo - Current Opinion in Plant …, 2022 - Elsevier
Plants produce a large number of diverse metabolites when they grow and develop as well
as when they respond to the changing external environment. These are an important source …

Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by …

H Deng, Y Gao, V Trappetti, D Hertig… - Cellular and Molecular …, 2022 - Springer
Once considered a waste product of anaerobic cellular metabolism, lactate has been
identified as a critical regulator of tumorigenesis, maintenance, and progression. The …

The INCREASE project: Intelligent Collections of food‐legume genetic resources for European agrofood systems

E Bellucci, O Mario Aguilar, S Alseekh, K Bett… - The Plant …, 2021 - Wiley Online Library
Food legumes are crucial for all agriculture‐related societal challenges, including climate
change mitigation, agrobiodiversity conservation, sustainable agriculture, food security and …

Acidic methanol treatment facilitates matrix-assisted laser desorption ionization-mass spectrometry imaging of energy metabolism

W Lu, NR Park, T TeSlaa, CSR Jankowski… - Analytical …, 2023 - ACS Publications
Detection of small molecule metabolites (SMM), particularly those involved in energy
metabolism using MALDI-mass spectrometry imaging (MSI), is challenging due to factors …

[HTML][HTML] Metabolomics and modelling approaches for systems metabolic engineering

JK Khanijou, H Kulyk, C Bergès, LW Khoo, P Ng… - Metabolic Engineering …, 2022 - Elsevier
Metabolic engineering involves the manipulation of microbes to produce desirable
compounds through genetic engineering or synthetic biology approaches. Metabolomics …

Progress and opportunities in microbial community metabolomics

A Bhosle, Y Wang, EA Franzosa… - Current Opinion in …, 2022 - Elsevier
Highlights•Microbiome-associated metabolite pools aid discovery of novel functions.•Guilt-
by-association approaches identify microbial derivatives of standard metabolites.•Machine …

Inherently hydrophilic mesoporous channel coupled with metal oxide for fishing endogenous salivary glycopeptides and phosphopeptides

Z Xu, Y Wu, X Hu, C Deng, N Sun - Chinese Chemical Letters, 2022 - Elsevier
Both glycosylation and phosphorylation exert crucial rule in multitudinous biological
processes. For in-depth profiling of glycosylation and phosphorylation, a magnetic metal …