Mounting evidence indicates that dysregulation of gap junctions and their structural subunits—
connexins—often occurs in, and sometimes causes, a variety of proliferative disorders …

This “Commentary” has examined the use of human stem cells for detection of toxicities of
physical, chemical, and biological toxins/toxicants in response to the challenge posed by the …

Dysregulation of gap junction intercellular communication (GJIC) is recognized as one of the
key hallmarks for identifying non-genotoxic carcinogens (NGTxC). Currently, there is a …

Many recent epidemiological, clinical and experimental findings support the hypothesis that
environmental toxicants are responsible for the increasing male reproductive disorders …

The activities of individual cells must be tightly coordinated in order to build and maintain
complex 3-dimensional body structures during embryogenesis and regeneration. Thus, one …

Prostate cancer is a prevalent disease that is characterized by a presumably long latency
period and a moderate propensity to metastasize. Although a range of mechanisms have …

The extreme aggressiveness of pancreatic ductal adenocarcinoma (PDA) has been
associated with blocked gap junctional intercellular communication (GJIC) and the presence …

The aim of the present study was to clarify the mechanisms of cell death induced by heavy‐
ion irradiation focusing on the bystander effect in human lung cancer A549 cells. In …

Abstract Cylindrospermopsis raciborskii (Nostocales, Cyanobacteria) has worldwide
distribution and is well known for producing the toxic alkaloid, cylindrospermopsin (CYN) …

Plant polyphenols including flavonoids and tannins are important constituent of our
everyday diet and medical herbals. It is broadly accepted that polyphenols may protect us …