Gap junctional signaling in pattern regulation: physiological network connectivity instructs growth and form

J Mathews, M Levin - Developmental neurobiology, 2017 - Wiley Online Library
Gap junctions (GJs) are aqueous channels that allow cells to communicate via physiological
signals directly. The role of gap junctional connectivity in determining single‐cell functions …

Natural phenolic antioxidants in bioanalytical chemistry: State of the art and prospects of development

GK Ziyatdinova, HC Budnikov - Russian Chemical Reviews, 2015 - iopscience.iop.org
Published data of the last decade on the chemical analysis and related problems of
investigation of phenolic antioxidants as components of complex biomedical and food …

[HTML][HTML] Exploring instructive physiological signaling with the bioelectric tissue simulation engine

A Pietak, M Levin - Frontiers in bioengineering and biotechnology, 2016 - frontiersin.org
Bioelectric cell properties have been revealed as powerful targets for modulating stem cell
function, regenerative response, developmental patterning, and tumor reprograming. Spatio …

Connexin and pannexin channels in cancer

JX Jiang, S Penuela - BMC cell biology, 2016 - Springer
Communication among cells via direct cell-cell contact by connexin gap junctions, or
between cell and extracellular environment via pannexin channels or connexin …

Cell systems bioelectricity: how different intercellular gap junctions could regionalize a multicellular aggregate

A Riol, J Cervera, M Levin, S Mafe - Cancers, 2021 - mdpi.com
Simple Summary Electric potential patterns across tissues are instructive for development,
regeneration, and tumorigenesis because they can influence transcription, migration, and …

Pharmacological modulation of connexin‐formed channels in cardiac pathophysiology

E De Vuyst, K Boengler, G Antoons… - British journal of …, 2011 - Wiley Online Library
Coordinated electrical activity in the heart is supported by gap junction channels located at
the intercalated discs of cardiomyocytes. Impaired gap junctional communication between …

Gap junction intercellular communication in the carcinogenesis hallmarks: is this a phenomenon or epiphenomenon?

R Zefferino, C Piccoli, S Di Gioia, N Capitanio… - Cells, 2019 - mdpi.com
If occupational tumors are excluded, cancer causes are largely unknown. Therefore, it
appeared useful to work out a theory explaining the complexity of this disease. More than …

Multiscale memory and bioelectric error correction in the cytoplasm–cytoskeleton‐membrane system

C Fields, M Levin - Wiley Interdisciplinary Reviews: Systems …, 2018 - Wiley Online Library
A fundamental aspect of life is the modification of anatomy, physiology, and behavior in the
face of changing conditions. This is especially illustrated by the adaptive regulation of …

Effects of the tributyltin on the blood parameters, immune responses and thyroid hormone system in zebrafish

ZH Li, P Li - Environmental Pollution, 2021 - Elsevier
Tributyltin (TBT) is a widely used organotin compound around the world and was frequently
detected in surface waters, which would pose risk to aquatic organisms. However, the …

Cancer stem cells and cancer nonstem cells: from adult stem cells or from reprogramming of differentiated somatic cells

JE Trosko - Veterinary pathology, 2009 - journals.sagepub.com
Two opposing hypotheses of the origin of cancer have existed for many decades. One
hypothesis postulates that the adult stem cell is needed to initiate the carcinogenic process …