Diagnosis and management of pediatric autoimmune liver disease: ESPGHAN hepatology committee position statement
G Mieli-Vergani, D Vergani, U Baumann… - Journal of pediatric …, 2018 - journals.lww.com
Paediatric autoimmune liver disease is characterized by inflammatory liver histology,
circulating autoantibodies, and increased levels of IgG, in the absence of a known etiology …
circulating autoantibodies, and increased levels of IgG, in the absence of a known etiology …
The natural history of primary sclerosing cholangitis in 781 children: a multicenter, international collaboration
MR Deneau, W El‐Matary, PL Valentino, R Abdou… - …, 2017 - Wiley Online Library
There are limited data on the natural history of primary sclerosing cholangitis (PSC) in
children. We aimed to describe the disease characteristics and long‐term outcomes of …
children. We aimed to describe the disease characteristics and long‐term outcomes of …
Autoimmune hepatitis, sclerosing cholangitis, and autoimmune sclerosing cholangitis or overlap syndrome
N Kerkar, A Chan - Clinics in liver disease, 2018 - liver.theclinics.com
Autoimmune liver disease in pediatrics encompasses autoimmune hepatitis (AIH),
autoimmune overlap with sclerosing cholangitis (SC), recurrence of AIH after liver …
autoimmune overlap with sclerosing cholangitis (SC), recurrence of AIH after liver …
[PDF][PDF] Lipid remodeling in hepatocyte proliferation and hepatocellular carcinoma
Background and Aims Hepatocytes undergo profound metabolic rewiring when primed to
proliferate during compensatory regeneration and in hepatocellular carcinoma (HCC) …
proliferate during compensatory regeneration and in hepatocellular carcinoma (HCC) …
[HTML][HTML] Treatment of primary sclerosing cholangitis in children
TJ Laborda, MK Jensen, M Kavan… - World journal of …, 2019 - ncbi.nlm.nih.gov
Primary sclerosing cholangitis (PSC) is a rare disease of stricturing and destruction of the
biliary tree with a complex genetic and environmental etiology. Most patients have co …
biliary tree with a complex genetic and environmental etiology. Most patients have co …
Defining primary sclerosing cholangitis: results from an international primary sclerosing cholangitis study group consensus process
CY Ponsioen, DN Assis, KM Boberg, CL Bowlus… - …, 2021 - gastrojournal.org
Although patients with PSC are increasingly diagnosed at earlier stages of disease based
on asymptomatic serum liver enzyme abnormalities, at least 45% of patients PSC present …
on asymptomatic serum liver enzyme abnormalities, at least 45% of patients PSC present …
The Sclerosing Cholangitis Outcomes in Pediatrics (SCOPE) index: a prognostic tool for children
Background and Aims Disease progression in children with primary sclerosing cholangitis
(PSC) is variable. Prognostic and risk‐stratification tools exist for adult‐onset PSC, but not …
(PSC) is variable. Prognostic and risk‐stratification tools exist for adult‐onset PSC, but not …
[PDF][PDF] Gamma glutamyltransferase reduction is associated with favorable outcomes in pediatric primary sclerosing cholangitis
Adverse clinical events in primary sclerosing cholangitis (PSC) happen too slowly to capture
during clinical trials. Surrogate endpoints are needed, but no such validated endpoints exist …
during clinical trials. Surrogate endpoints are needed, but no such validated endpoints exist …
The intestinal microbiome and paediatric liver disease
DH Leung, D Yimlamai - The Lancet Gastroenterology & Hepatology, 2017 - thelancet.com
The intestinal microbiome has been the intense focus of recent study, but how the microbiota
affects connected organs, such as the liver, has not been fully elucidated. The microbiome …
affects connected organs, such as the liver, has not been fully elucidated. The microbiome …
Clinical features and MRI progression of small duct primary sclerosing cholangitis (PSC)
Purpose First, to evaluate and describe the clinical and MRI progression of patients with
small duct primary sclerosing cholangitis (sdPSC), and second, to look for MRI features …
small duct primary sclerosing cholangitis (sdPSC), and second, to look for MRI features …