Emerging roles for the gut microbiome in autism spectrum disorder

HE Vuong, EY Hsiao - Biological psychiatry, 2017 - Elsevier
Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder that affects one
in 45 children in the United States, with a similarly striking prevalence in countries around …

A systematic review of structural MRI biomarkers in autism spectrum disorder: A machine learning perspective

AM Pagnozzi, E Conti, S Calderoni, J Fripp… - International Journal of …, 2018 - Elsevier
Abstract Autism Spectrum Disorder (ASD) affects approximately 1% of the population and
leads to impairments in social interaction, communication and restricted, repetitive …

Synaptic and transcriptionally downregulated genes are associated with cortical thickness differences in autism

R Romero-Garcia, V Warrier, ET Bullmore… - Molecular …, 2019 - nature.com
Differences in cortical morphology—in particular, cortical volume, thickness and surface
area—have been reported in individuals with autism. However, it is unclear what aspects of …

Differences in subcortico-cortical interactions identified from connectome and microcircuit models in autism

B Park, SJ Hong, SL Valk, C Paquola… - Nature …, 2021 - nature.com
The pathophysiology of autism has been suggested to involve a combination of both
macroscale connectome miswiring and microcircuit anomalies. Here, we combine …

A normative modelling approach reveals age-atypical cortical thickness in a subgroup of males with autism spectrum disorder

RAI Bethlehem, J Seidlitz, R Romero-Garcia… - Communications …, 2020 - nature.com
Understanding heterogeneity is an important goal on the path to precision medicine for
autism spectrum disorders (ASD). We examined how cortical thickness (CT) in ASD can be …

Anomalous brain gyrification patterns in major psychiatric disorders: a systematic review and transdiagnostic integration

D Sasabayashi, T Takahashi, Y Takayanagi… - Translational …, 2021 - nature.com
Anomalous patterns of brain gyrification have been reported in major psychiatric disorders,
presumably reflecting their neurodevelopmental pathology. However, previous reports …

Multidimensional neuroanatomical subtyping of autism spectrum disorder

SJ Hong, SL Valk, A Di Martino, MP Milham… - Cerebral …, 2018 - academic.oup.com
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders with multiple
biological etiologies and highly variable symptoms. Using a novel analytical framework that …

Cell-specific gene-expression profiles and cortical thickness in the human brain

J Shin, L French, T Xu, G Leonard, M Perron… - Cerebral …, 2018 - academic.oup.com
Neurobiological underpinnings of cortical thickness in the human brain are largely unknown.
Here we use cell-type-specific gene markers to evaluate the contribution of 9 neural cell …

Toward a better understanding of neuronal migration deficits in autism spectrum disorders

YH Pan, N Wu, XB Yuan - Frontiers in cell and developmental biology, 2019 - frontiersin.org
Newborn neurons in developing brains actively migrate from germinal zones to designated
regions before being wired into functional circuits. The motility and trajectory of migrating …

Anomalous morphology in left hemisphere motor and premotor cortex of children who stutter

EO Garnett, HM Chow, A Nieto-Castañón, JA Tourville… - Brain, 2018 - academic.oup.com
Stuttering is a neurodevelopmental disorder that affects the smooth flow of speech
production. Stuttering onset occurs during a dynamic period of development when children …