Extracellular matrix (ECM) collectively represents a class of naturally derived proteinaceous
biomaterials purified from harvested organs and tissues with increasing scientific focus and …

According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

Recent advances in next-generation DNA sequencing and proteomics provide an
unprecedented ability to survey mRNA and protein abundances. Such proteome-wide …

In this Perspective, we discuss developments in mass-spectrometry-based proteomic
technology over the past decade from the viewpoint of our laboratory. We also reflect on …

Mass-spectrometry-based proteomics is continuing to make major contributions to the
discovery of fundamental biological processes and, more recently, has also developed into …

The parallel reaction monitoring (PRM) assay has emerged as an alternative method of
targeted quantification. The PRM assay is performed in a high resolution and high mass …

Biological tissues exhibit complex spatial heterogeneity that directs the functions of
multicellular organisms. Quantifying protein expression is essential for elucidating …

The ability to reliably and reproducibly measure any protein of the human proteome in any
tissue or cell type would be transformative for understanding systems-level properties as …

Efficient analysis of very large amounts of raw data for peptide identification and protein
quantification is a principal challenge in mass spectrometry (MS)-based proteomics. Here …

This document contains recommendations for terminology in mass spectrometry.
Development of standard terms dates back to 1974 when the IUPAC Commission on …