[HTML][HTML] miR-301a suppression within fibroblasts limits the progression of fibrosis through the TSC1/mTOR pathway

J Wang, X Li, M Zhong, Y Wang, L Zou, M Wang… - … Therapy-Nucleic Acids, 2020 - cell.com
Pulmonary fibrosis has been characterized by abnormal proliferation of fibroblasts and
massive deposition of the extracellular matrix, which results from a complex interplay of …

TSG-6 secreted by mesenchymal stem cells suppresses immune reactions influenced by BMP-2 through p38 and MEK mitogen-activated protein kinase pathway

S Um, HY Kim, JH Lee, IS Song, BM Seo - Cell and tissue research, 2017 - Springer
Abstract Bone morphogenetic protein 2 (BMP-2) has a critical function in bone and cartilage
development and in repairing damaged organs and tissue. However, clinical use of BMP-2 …

Telocytes and lung disease

D Song, D Cretoiu, SM Cretoiu, X Wang - 2016 - digitum.um.es
Telocytes (TCs) represent a new distinct type of interstitial cells found in many organs,
including lungs. TCs are mainly defined by a small cellular body from which arise very long …

Risk factors and changes of peripheral NK and T cells in pulmonary interstitial fibrosis of patients with rheumatoid arthritis

NL Lai, W Jia, X Wang, J Luo, GY Liu… - Canadian respiratory …, 2019 - Wiley Online Library
Objective. The absolute and relative changes of peripheral NK and T subsets are unclear in
rheumatoid arthritis (RA) associated with pulmonary interstitial fibrosis (RA‐ILD). To …

Notch signaling pathway mediates the immunomodulatory mechanism of Yangfei Huoxue decoction alleviating bleomycin-induced pulmonary fibrosis in rats.

C Hui, L Xiao, S Yinxu, C Ke… - Journal of …, 2020 - search.ebscohost.com
OBJECTIVE: To investigate the immunomodulatory mechanism by which Yangfei Huoxue
decoction (YHD) alleviates bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats …

[HTML][HTML] Promising Therapeutic Effects of Embryonic Stem Cells-Origin Mesenchymal Stem Cells in Experimental Pulmonary Fibrosis Models: Immunomodulatory and …

H Lee, OY Jeong, HJ Park, SL Lee, E Bok, M Kim… - Immune …, 2023 - ncbi.nlm.nih.gov
Interstitial lung disease (ILD) involves persistent inflammation and fibrosis, leading to
respiratory failure and even death. Adult tissue-derived mesenchymal stem cells (MSCs) …

Regulatory mechanism of the induction of regulatory T cells through growth factors released by human mesenchymal stem cells

I Miyagawa, S Nakayamada, M Kondo… - Critical Reviews™ in …, 2018 - dl.begellhouse.com
Mesenchymal stem cells (MSCs) undergo self-renewal and differentiation into multiple
lineages. They exert anti-inflammatory and immunomodulatory effects via either cell–cell …

[PDF][PDF] CD4+ LAG3+ T cells are decreased in SSc-ILD and affect fibroblast mesenchymal transition by TGF-β3

L Qin, H Lin, F Zhu, J Wang, T Feng, T Xu, G Zhang… - Iscience, 2023 - cell.com
Pulmonary fibrosis frequently occurs in rheumatic conditions, particularly systemic sclerosis-
associated interstitial lung disease (SSc-ILD). The pathology involves cell transformation …

Interferon-γ suppresses the proliferation and migration of human placenta-derived mesenchmal stromal cells and enhances their ability to induce the generation of …

JZ Yi, ZH Chen, FH Xu, ZY Wang, HQ Zhang… - Cellular …, 2018 - Elsevier
We investigate the effects of interferon (IFN)-γ on human placenta-derived mesenchymal
stromal cells (hPMSCs), in particular, their adhesion, proliferation and migration and …

Stem cells in lung repair and regeneration: current applications and future promise

Y Zhu, X Chen, X Yang… - Journal of Cellular …, 2018 - Wiley Online Library
Lung diseases are major cause of morbidity and mortality worldwide. The progress in
regenerative medicine and stem cell research in the lung are currently a fast‐growing …