Cardiac 123I-metaiodobenzylguanidine (MIBG) scintigraphy in Parkinson's disease: A comprehensive review

J Pitton Rissardo, AL Fornari Caprara - Brain Sciences, 2023 - mdpi.com
Cardiac sympathetic denervation, as documented on 123I-metaiodobenzylguanidine (MIBG)
myocardial scintigraphy, is relatively sensitive and specific for distinguishing Parkinson's …

Impaired meningeal lymphatic drainage in patients with idiopathic Parkinson's disease

XB Ding, XX Wang, DH Xia, H Liu, HY Tian, Y Fu… - Nature medicine, 2021 - nature.com
Animal studies implicate meningeal lymphatic dysfunction in the pathogenesis of
neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease (PD) …

Clinical trials in dementia with Lewy bodies: the evolving concept of co-pathologies, patient selection and biomarkers

LL Gibson, C Abdelnour, J Chong… - Current Opinion in …, 2023 - journals.lww.com
Clinical trials in dementia with Lewy bodies: the evolving c... : Current Opinion in Neurology
Clinical trials in dementia with Lewy bodies: the evolving concept of co-pathologies, patient …

Proteomic comparison between non‐purified cerebrospinal fluid and cerebrospinal fluid‐derived extracellular vesicles from patients with Alzheimer's, Parkinson's and …

Y Hirschberg, N Valle‐Tamayo… - Journal of …, 2023 - Wiley Online Library
Dementia is a leading cause of death worldwide, with increasing prevalence as global life
expectancy increases. The most common neurodegenerative disorders are Alzheimer's …

Neurofilament light chain is increased in the parahippocampal cortex and associates with pathological hallmarks in Parkinson's disease dementia

I Frigerio, MA Laansma, CP Lin, EJM Hermans… - Translational …, 2023 - Springer
Background Increased neurofilament levels in biofluids are commonly used as a proxy for
neurodegeneration in several neurodegenerative disorders. In this study, we aimed to …

Mechanisms of neurodegeneration in various forms of parkinsonism—Similarities and differences

D Koziorowski, M Figura, ŁM Milanowski, S Szlufik… - Cells, 2021 - mdpi.com
Parkinson's disease (PD), dementia with Lewy body (DLB), progressive supranuclear palsy
(PSP), corticobasal degeneration (CBD) and multiple system atrophy (MSA) belong to a …

Clinical biomarkers for Lewy body diseases

MM Abdelmoaty, E Lu, R Kadry, EG Foster, S Bhattarai… - Cell & Bioscience, 2023 - Springer
Synucleinopathies are a group of neurodegenerative disorders characterized by pathologic
aggregates of neural and glial α-synuclein (α-syn) in the form of Lewy bodies (LBs), Lewy …

Latest advances in mechanisms of epileptic activity in Alzheimer's disease and dementia with Lewy Bodies

M Vicente, K Addo-Osafo, K Vossel - Frontiers in neurology, 2024 - frontiersin.org
Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) stand as the prevailing
sources of neurodegenerative dementia, impacting over 55 million individuals across the …

The promise of amplification assays for accurate early detection of α-synucleinopathies: a review

R Kurapova, L Chouliaras, JT O'Brien - Experimental Gerontology, 2022 - Elsevier
Lewy body dementia encompasses the common neurodegenerative disorders Dementia
with Lewy bodies (DLB) and Parkinson's disease dementia (PDD). Lewy Body disease …

Progressive olfactory impairment and cardiac sympathetic denervation in REM sleep behavior disorder

A Janzen, D Vadasz, J Booij, M Luster… - Journal of …, 2022 - content.iospress.com
Background: Isolated rapid eye movement sleep behavior disorder (iRBD) is prodromal for
Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Objective: We investigated …