This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …

This narrative state-of-the-art review paper describes the progress in the understanding and
treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific …

Cannabidiol (CBD), a major non-psychoactive phytocannabinoid in cannabis, is an effective
treatment for some forms of epilepsy and pain. At high concentrations, CBD interacts with a …

Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

In recent years, the interest in cannabidiol (CBD) has increased because of the lack of
psychoactive properties. However, CBD has low solubility and bioavailability, variable …

The incidence of chronic pain is high in the general population and it is closely related to
anxiety disorders, which promote negative effects on the quality of life. The cannabinoid …

Rationale Cannabis-based medicinal products (CBMPs) have been identified as novel
therapeutics for generalised anxiety disorder (GAD) based on pre-clinical models; however …

Abstract Combination tetrahydrocannabinol (THC)/cannabidiol (CBD) medicines or CBD-
only medicines are prospective treatments for chronic pain, stress, anxiety, depression, and …

Natural products (NPs) have consistently played a pivotal role in pharmaceutical research,
exerting profound impacts on the treatment of human diseases. A significant proportion of …

Hypothesis Lipophilic cannabidiol can be solubilized in oil-in water nanoemulsions, which
can then be impregnated into chitosan hydrogels forming another colloidal system that will …