Clinical outcome assessment trends in clinical trials—Contrasting oncology and non‐oncology trials

Y Kim, MR Gilbert, TS Armstrong, O Celiku - Cancer Medicine, 2023 - Wiley Online Library
Abstract Background Clinical outcome assessments (COAs) are key to patient‐centered
evaluation of novel interventions and supportive care. COAs are particularly informative in …

Patient‐reported outcomes provide prognostic information for survival in patients with diffuse large B‐cell lymphoma: Analysis of 1239 patients from the GOYA study

H Huang, A Datye, M Fan, A Knapp, T Nielsen… - Cancer …, 2022 - Wiley Online Library
Purpose We investigated the prognostic value of pretreatment patient‐reported outcomes
(PROs) in patients with diffuse large B‐cell lymphoma (DLBCL) receiving obinutuzumab …

[HTML][HTML] Implementation of a model integrating primary and oncology pharmacists' care for patients taking oral anticancer agents (OAA)

KB Farris, T Cadwallader, J Farley, K Gatwood… - Exploratory Research in …, 2022 - Elsevier
Improvements in chronic myeloid leukemia (CML), chronic lymphocytic leukemia (CLL), and
multiple myeloma (MM) treatment options have increased the 5-year survival rates for …

Online platform to assess complex social relationships and patient-reported outcomes among adolescent and young adult cancer survivors

PG Poudel, HE Bauer, DK Srivastava… - JCO Clinical Cancer …, 2021 - ascopubs.org
PURPOSE Social integration and relationship issues have been understudied among
adolescent and young adult (AYA) cancer survivors. This study compared social …

Defining and Addressing Research Priorities in Cancer Cachexia through Transdisciplinary Collaboration

MA Park, CJ Whelan, S Ahmed, T Boeringer, J Brown… - Cancers, 2024 - mdpi.com
For many patients, the cancer continuum includes a syndrome known as cancer-associated
cachexia (CAC), which encompasses the unintended loss of body weight and muscle mass …

[HTML][HTML] Association of change in health-related quality of life and treatment discontinuation in metastatic breast cancer: a post hoc, exploratory analysis of two …

T Kawahara, T Iwamoto, I Takashima… - Supportive Care in …, 2022 - Springer
Purpose Identifying factors associated with treatment alteration (treatment discontinuation
and dose reduction) may help to attain the treatment goals for metastatic breast cancer. The …

[HTML][HTML] 15 years of patient-reported outcomes in clinical trials leading to GU cancer drug approvals: a systematic review on the quality of data reporting and analysis

M Paravathaneni, H Safa, V Joshi, MK Tamil… - …, 2024 - thelancet.com
Background Standardized, high-quality PRO data reporting is crucial for patient centered
care in the field of oncology, especially in clinical trials that establish standard of care. This …

[HTML][HTML] Patient-reported outcome measures used in routine care predict for survival at disease progression in patients with advanced lung cancer

RB Friis, NH Hjøllund, H Pappot, GA Taarnhøj… - Clinical Lung Cancer, 2021 - Elsevier
Background Patient-reported outcome (PRO) measures are increasingly being implemented
in routine care to aid in clinical decision-making. However, the prognostic value of PRO …

Influencing factors of treatment and prognosis perceptions among advanced cancer patients: a cross-sectional study

B Hu, X Yin, C Du, H Zhu, Z Gao, X Zhu… - Supportive Care in Cancer, 2022 - Springer
Purpose The present study aimed to investigate the status and significantly influencing
factors of treatment and prognosis perceptions among advanced cancer patients based on …

Quality of life independently predicts overall survival in myelofibrosis: Key insights from the COntrolled MyeloFibrosis Study with ORal Janus kinase inhibitor Treatment …

HE Kosiorek, RM Scherber, HL Geyer… - British journal of …, 2022 - par.nsf.gov
Patient-reported outcomes (PROs) have considerable value for survival prediction, and
generally include both quality of life (QOL) and symptom measures. A recent metaanalysis of …