[HTML][HTML] The prognostic significance of circulating plasma cells in newly diagnosed multiple myeloma patients

W Yao, H Yang, H You, J Shang, Y Zhai, Z Yan… - Frontiers in …, 2023 - frontiersin.org
Objective Multiple myeloma (MM) is a highly characteristic tumor that is influenced by
numerous factors that determine its prognosis. Studies indicate that the presence of …

[HTML][HTML] Phase II study of carfilzomib, thalidomide, and low-dose dexamethasone as induction and consolidation in newly diagnosed, transplant eligible patients with …

R Wester, B Van Der Holt, E Asselbergs… - …, 2019 - ncbi.nlm.nih.gov
This is a phase II dose escalation trial of carfilzomib in combination with thalidomide and
dexamethasone for induction and consolidation in transplant-eligible patients with newly …

[HTML][HTML] Molecular Long-Term Analysis of the GMMG-HD4 Trial in Multiple Myeloma—Patterns of Association of Chromosomal Aberrations with Response and …

A Seckinger, H Salwender, H Martin, C Scheid… - International Journal of …, 2024 - mdpi.com
Based on the lack of differences in progression-free and overall survival after a median
follow-up of 93 months in our HOVON-65/GMMG-HD4 trial (German part; n= 395) …

Ixazomib maintenance therapy in newly diagnosed multiple myeloma: an integrated analysis of four phase I/II studies

MA Dimopoulos, JP Laubach… - European Journal of …, 2019 - Wiley Online Library
Objectives To evaluate the safety and efficacy of maintenance therapy with the oral
proteasome inhibitor ixazomib in patients with newly diagnosed multiple myeloma (NDMM) …

Upfront stem cell transplantation for newly diagnosed multiple myeloma with del (17p) and t (4; 14): a study from the CMWP-EBMT

N Gagelmann, DJ Eikema, LC De Wreede… - Bone marrow …, 2021 - nature.com
We analyzed newly diagnosed multiple myeloma patients with del (17p) and/or t (4; 14)
undergoing either upfront single autologous (auto), tandem autologous (auto-auto) or …

[HTML][HTML] Lenalidomide or bortezomib as maintenance treatment remedy the inferior impact of high-risk cytogenetic abnormalities in non-transplant patients with newly …

Z Zhuang, Y Tian, L Shi, D Zou, R Feng, W Tian… - Frontiers in …, 2023 - frontiersin.org
Maintenance treatment is a pivotal part in the whole process management of multiple
myeloma (MM), which further deepens response and improves survival. However, evidence …

[HTML][HTML] Bortezomib-based induction, high-dose melphalan and lenalidomide maintenance in myeloma up to 70 years of age

EK Mai, K Miah, U Bertsch, J Dürig, C Scheid… - Leukemia, 2021 - nature.com
Intensive upfront therapy in newly-diagnosed multiple myeloma (MM) including induction
therapy (IT), high-dose melphalan (MEL200), and autologous blood stem cell …

[HTML][HTML] Prolonged lenalidomide therapy does not impact autologous peripheral blood stem cell mobilization and collection in multiple myeloma patients: a single …

AJ Cowan, PA Stevenson, DJ Green, S Tuazon… - … and cellular therapy, 2021 - Elsevier
Since the introduction of lenalidomide into induction therapy for multiple myeloma (MM),
there have been conflicting reports about its impact on autologous peripheral blood stem …

Kidney Transplantation in Multiple Myeloma and Monoclonal Gammopathy of Renal Significance

N Leung, C Heybeli - Seminars in Nephrology, 2024 - Elsevier
Recent advances in the treatment of plasma cell disorders (PCDs) have provided a wealth of
therapy alternatives and improved overall survival tremendously. Various types of PCDs are …

Newly diagnosed multiple myeloma: making sense of the menu

CL Costello - Hematology, 2022 - ashpublications.org
The development of new drugs and subsequent novel combinations for the treatment of
newly diagnosed multiple myeloma (NDMM) has resulted in a plethora of treatment options …