The continued threat of emerging flaviviruses
TC Pierson, MS Diamond - Nature microbiology, 2020 - nature.com
Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …
populations and cause a spectrum of potentially severe diseases including hepatitis …
The emergence of Zika virus and its new clinical syndromes
TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …
threat because of its potential to generate explosive epidemics and ability to cause …
Evasion of type I interferon by SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication and host
immune response determine coronavirus disease 2019 (COVID-19), but studies evaluating …
immune response determine coronavirus disease 2019 (COVID-19), but studies evaluating …
Viral innate immune evasion and the pathogenesis of emerging RNA virus infections
T Nelemans, M Kikkert - Viruses, 2019 - mdpi.com
Positive-sense single-stranded RNA (+ ssRNA) viruses comprise many (re-) emerging
human pathogens that pose a public health problem. Our innate immune system and, in …
human pathogens that pose a public health problem. Our innate immune system and, in …
Pathogenesis of Zika virus infection
MI Giraldo, M Gonzalez-Orozco… - Annual Review of …, 2023 - annualreviews.org
Zika virus (ZIKV) is an emerging virus from the Flaviviridae family that is transmitted to
humans by mosquito vectors and represents an important health problem. Infections in …
humans by mosquito vectors and represents an important health problem. Infections in …
Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains
The global emergence of Zika virus (ZIKV) revealed the unprecedented ability for a mosquito-
borne virus to cause congenital birth defects. A puzzling aspect of ZIKV emergence is that all …
borne virus to cause congenital birth defects. A puzzling aspect of ZIKV emergence is that all …
Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS 1‐caspase‐1 axis
Viral infection triggers host innate immune responses, which primarily include the activation
of type I interferon (IFN) signaling and inflammasomes. Here, we report that Zika virus (ZIKV) …
of type I interferon (IFN) signaling and inflammasomes. Here, we report that Zika virus (ZIKV) …
Antiviral strategies targeting host factors and mechanisms obliging+ ssRNA viral pathogens
The ongoing COVID-19 pandemic, periodic recurrence of viral infections, and the
emergence of challenging variants has created an urgent need of alternative therapeutic …
emergence of challenging variants has created an urgent need of alternative therapeutic …
Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease
The limited host tropism of numerous viruses causing disease in humans remains
incompletely understood. One example is Zika virus (ZIKV), an RNA virus that has …
incompletely understood. One example is Zika virus (ZIKV), an RNA virus that has …
The evolution of Zika virus from Asia to the Americas
Zika virus (ZIKV) was once considered an obscure member of the large and diverse family of
mosquito-borne flaviviruses, and human infections with ZIKV were thought to be sporadic …
mosquito-borne flaviviruses, and human infections with ZIKV were thought to be sporadic …