[HTML][HTML] Probing molecular insights into Zika virus–host interactions

I Lee, S Bos, G Li, S Wang, G Gadea, P Desprès… - Viruses, 2018 - mdpi.com
The recent Zika virus (ZIKV) outbreak in the Americas surprised all of us because of its rapid
spread and association with neurologic disorders including fetal microcephaly, brain and …

[HTML][HTML] C19orf66 interrupts Zika virus replication by inducing lysosomal degradation of viral NS3

Y Wu, X Yang, Z Yao, X Dong, D Zhang… - PLoS neglected …, 2020 - journals.plos.org
The rapidly emerging human health crisis associated with the Zika virus (ZIKV) epidemic
and its link to severe complications highlights the growing need to identify the mechanisms …

Binding of duck Tembusu virus nonstructural protein 2A to duck STING disrupts induction of its signal transduction cascade to inhibit beta interferon induction

W Zhang, B Jiang, M Zeng, Y Duan, Z Wu… - Journal of …, 2020 - Am Soc Microbiol
Duck Tembusu virus (DTMUV), which is similar to other mosquito-borne flaviviruses that
replicate well in most mammalian cells, is an emerging pathogenic flavivirus that has caused …

The Epidermal Growth Factor Receptor Is a Relevant Host Factor in the Early Stages of The Zika Virus Life Cycle In Vitro

C Sabino, D Bender, ML Herrlein, E Hildt - Journal of virology, 2021 - Am Soc Microbiol
Zika virus (ZIKV) is a flavivirus that is well known for the epidemic in the Americas in 2015
and 2016 in which microcephaly in newborns and other neurological complications were …

[HTML][HTML] The molecular interactions of ZIKV and DENV with the type-I IFN response

RC Coldbeck-Shackley, NS Eyre, MR Beard - Vaccines, 2020 - mdpi.com
Zika Virus (ZIKV) and Dengue Virus (DENV) are related viruses of the Flavivirus genus that
cause significant disease in humans. Existing control measures have been ineffective at …

Human type I interferon antiviral effects in respiratory and reemerging viral infections

PL Acosta, AB Byrne, DR Hijano… - Journal of immunology …, 2020 - Wiley Online Library
Type I interferons (IFN‐I) are a group of related proteins that help regulate the activity of the
immune system and play a key role in host defense against viral infections. Upon infection …

Antibodies elicited by an NS1-based vaccine protect mice against Zika virus

MJ Bailey, F Broecker, J Duehr, F Arumemi, F Krammer… - MBio, 2019 - Am Soc Microbiol
Zika virus is a mosquito-borne flavivirus which can cause severe disease in humans,
including microcephaly and other congenital malformations in newborns and Guillain-Barré …

[HTML][HTML] NS5 conservative site is required for Zika virus to restrict the RIG-I signaling

A Li, W Wang, Y Wang, K Chen, F Xiao, D Hu… - Frontiers in …, 2020 - frontiersin.org
During host–virus co-evolution, cells develop innate immune systems to inhibit virus
invasion, while viruses employ strategies to suppress immune responses and maintain …

[HTML][HTML] Efficient Dicer processing of virus-derived double-stranded RNAs and its modulation by RIG-I-like receptor LGP2

Y Zhang, Y Xu, Y Dai, Z Li, J Wang, Z Ye, Y Ren… - PLoS …, 2021 - journals.plos.org
The interferon-regulated antiviral responses are essential for the induction of both innate
and adaptive immunity in mammals. Production of virus-derived small-interfering RNAs …

[HTML][HTML] Host immune response against DENV and ZIKV infections

SD Sekaran, AA Ismail, G Thergarajan… - Frontiers in cellular …, 2022 - frontiersin.org
Dengue is a major public health concern, affecting almost 400 million people worldwide,
with about 70% of the global burden of disease in Asia. Despite revised clinical …