Ion homeostasis is extremely important for the survival of both normal as well as neoplastic
cells. The altered ion homeostasis found in cancer cells prompted the investigation of …

Emerging studies have shown that nigericin, an H+, K+ and Pb 2+ ionophore, has exhibited
a promising anti-cancer activity in various cancers. However, its anti-cancer mechanisms …

Background Neuroinflammation is a vital pathophysiological process during ischemic stroke.
Activated astrocytes play a major role in inflammation. Lipocalin-2 (LCN2), secreted by …

Ambient fine particulate matter (PM 2.5) is considered a leading cause of pathogenic
particulate matter induced lung injury. And Salidroside (Sal), the major bioactive constituent …

Exposure to particulate matter (PM) 2.5 in air pollution is a serious health issue worldwide.
At present, effective prevention measures and modalities of treatment for PM2. 5-caused …

Eleutheroside E (EE) is a primary active component of Acanthopanax senticosus, which has
been reported to inhibit the expression of inflammatory genes, but the underlying …

Introduction Dysregulation of NLRP3 inflammasome complex formation can promote chronic
inflammation by increased release of IL-1β. However, the effect of NLRP3 complex formation …

Exposure to fine particulate matter (PM2. 5), an environmental pollutant, significantly
contributes to the incidence of and risk of mortality associated with respiratory diseases …

Cancer cells have a more hyperpolarised mitochondrial membrane potential (ΨIM) than
normal cells. ΨIM=∼− 220 mV in cancer cells as compared to∼− 140 mV in normal cells …

Serglycin is a proteoglycan that was first found to be secreted by hematopoietic cells. As an
extracellular matrix (ECM) component, serglycin promotes nasopharyngeal carcinoma …