[HTML][HTML] Unraveling Molecular and Genetic Insights into Neurodegenerative Diseases: Advances in Understanding Alzheimer's, Parkinson's, and Huntington's …
AV Ciurea, AG Mohan, RA Covache-Busuioc… - International journal of …, 2023 - mdpi.com
Neurodegenerative diseases are, according to recent studies, one of the main causes of
disability and death worldwide. Interest in molecular genetics has started to experience …
disability and death worldwide. Interest in molecular genetics has started to experience …
[HTML][HTML] Mitochondria and brain disease: a comprehensive review of pathological mechanisms and therapeutic opportunities
VJ Clemente-Suárez, L Redondo-Flórez… - Biomedicines, 2023 - mdpi.com
Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …
Resource curse hypothesis and economic growth: A global analysis using bootstrapped panel quantile regression analysis
Y Guo, WK Wong, N Su, W Ghardallou, JCO Gavilán… - Resources Policy, 2023 - Elsevier
To achieve potential economic growth is a worldwide challenge. The mentioned study aims
to evaluate the impact of country's natural resources on economic growth. This analysis …
to evaluate the impact of country's natural resources on economic growth. This analysis …
LRRK2 suppresses lysosome degradative activity in macrophages and microglia through MiT-TFE transcription factor inhibition
N Yadavalli, SM Ferguson - Proceedings of the National …, 2023 - National Acad Sciences
Cells maintain optimal levels of lysosome degradative activity to protect against pathogens,
clear waste, and generate nutrients. Here, we show that LRRK2, a protein that is tightly …
clear waste, and generate nutrients. Here, we show that LRRK2, a protein that is tightly …
[HTML][HTML] Sphingolipids in neurodegenerative diseases
Neurodegenerative Diseases (NDDs) are a group of disorders that cause progressive
deficits of neuronal function. Recent evidence argues that sphingolipid metabolism is …
deficits of neuronal function. Recent evidence argues that sphingolipid metabolism is …
The lysosomal β-glucocerebrosidase strikes mitochondria: Implications for Parkinson's therapeutics
JC Rubilar, TF Outeiro, AD Klein - Brain, 2024 - academic.oup.com
Parkinson's disease (PD) is a neurodegenerative disorder primarily known for typical motor
features that arise due to the loss of dopaminergic neurons in the substantia nigra. However …
features that arise due to the loss of dopaminergic neurons in the substantia nigra. However …
[HTML][HTML] Older adults and individuals with Parkinson's disease control posture along suborthogonal directions that deviate from the traditional anteroposterior and …
A rich and complex temporal structure of variability in postural sway characterizes healthy
and adaptable postural control. However, neurodegenerative disorders such as Parkinson's …
and adaptable postural control. However, neurodegenerative disorders such as Parkinson's …
[HTML][HTML] The Role of Exercise in Maintaining Mitochondrial Proteostasis in Parkinson's Disease
J Li, Y Xu, T Liu, Y Xu, X Zhao, J Wei - International Journal of Molecular …, 2023 - mdpi.com
Parkinson's disease (PD) is the second most common rapidly progressive
neurodegenerative disease and has serious health and socio-economic consequences …
neurodegenerative disease and has serious health and socio-economic consequences …
[HTML][HTML] Molecular and cellular interactions in pathogenesis of sporadic Parkinson disease
LP Dolgacheva, VP Zinchenko… - International Journal of …, 2022 - mdpi.com
An increasing number of the population all around the world suffer from age-associated
neurodegenerative diseases including Parkinson's disease (PD). This disorder presents …
neurodegenerative diseases including Parkinson's disease (PD). This disorder presents …
The marine-derived compound TAG alleviates Parkinson's disease by restoring RUBCN-mediated lipid metabolism homeostasis
P Yang, Y Liu, Z Tong, Q Huang, X Xie, S Mao… - Acta Pharmacologica …, 2024 - nature.com
Parkinson's disease (PD) is the second most common neurodegenerative disease, and its
prevalence is increasing. Currently, no effective therapies for PD exist. Marine-derived …
prevalence is increasing. Currently, no effective therapies for PD exist. Marine-derived …