AU-rich elements: characterization and importance in mRNA degradation
CYA Chen, AB Shyu - Trends in biochemical sciences, 1995 - cell.com
Adenylate/uridylate-rich elements (AREs) are found in the 3′ untranslated region (UTR) of
many messenger RNAs (mRNAs) that code for proto-oncogenes, nuclear transcription …
many messenger RNAs (mRNAs) that code for proto-oncogenes, nuclear transcription …
The reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive and compulsive behaviors
K Blum, ER Braverman, JM Holder… - … of psychoactive drugs, 2000 - Taylor & Francis
The dopaminergic system, and in particular the dopamine D2 receptor, has been implicated
in reward mechanisms. The net effect of neurotransmitter interaction at the mesolimbic brain …
in reward mechanisms. The net effect of neurotransmitter interaction at the mesolimbic brain …
[PDF][PDF] RNA 5-methylcytosine facilitates the maternal-to-zygotic transition by preventing maternal mRNA decay
The maternal-to-zygotic transition (MZT) is a conserved and fundamental process during
which the maternal environment is converted to an environment of embryonic-driven …
which the maternal environment is converted to an environment of embryonic-driven …
The cap and poly (A) tail function synergistically to regulate mRNA translational efficiency.
DR Gallie - Genes & development, 1991 - genesdev.cshlp.org
The cap structure and the poly (A) tail are important regulatory determinants in establishing
the translational efficiency of a messenger RNA. Although the mechanism by which either …
the translational efficiency of a messenger RNA. Although the mechanism by which either …
Serum amyloid A, the major vertebrate acute‐phase reactant
CM Uhlar, AS Whitehead - European journal of biochemistry, 1999 - Wiley Online Library
The serum amyloid A (SAA) family comprises a number of differentially expressed
apolipoproteins, acute‐phase SAAs (A‐SAAs) and constitutive SAAs (C‐SAAs). A‐SAAs are …
apolipoproteins, acute‐phase SAAs (A‐SAAs) and constitutive SAAs (C‐SAAs). A‐SAAs are …
Engineered nucleic acids encoding a modified erythropoietin and their expression
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
46147671&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
46147671&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
mRNA stability in mammalian cells
J Ross - Microbiological reviews, 1995 - Am Soc Microbiol
This review concerns how cytoplasmic mRNA half-lives are regulated and how mRNA decay
rates influence gene expression. mRNA stability influences gene expression in virtually all …
rates influence gene expression. mRNA stability influences gene expression in virtually all …
Terminally modified RNA
T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49447811&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
49447811&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Regulation of mRNA stability in mammalian cells
J Guhaniyogi, G Brewer - Gene, 2001 - Elsevier
The regulation of mRNA decay is a major control point in gene expression. The stability of a
particular mRNA is controlled by specific interactions between its structural elements and …
particular mRNA is controlled by specific interactions between its structural elements and …
A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation.
CJ Decker, R Parker - Genes & development, 1993 - genesdev.cshlp.org
To determine pathways of mRNA turnover in yeast, we have followed the poly (A) tail
removal and degradation of a pulse of newly synthesized transcripts from four different …
removal and degradation of a pulse of newly synthesized transcripts from four different …